77947

Supelco

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid

analytical standard

Synonym(s):
Metoprolol acid, Atenolol acid, 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetic acid
Empirical Formula (Hill Notation):
C14H21NO4
CAS Number:
Molecular Weight:
267.32
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

analytical standard

assay

≥97.0% (HPLC)

CofA

certificate is enclosed in each package

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)NCC(O)COc1ccc(CC(O)=O)cc1

InChI

1S/C14H21NO4/c1-10(2)15-8-12(16)9-19-13-5-3-11(4-6-13)7-14(17)18/h3-6,10,12,15-16H,7-9H2,1-2H3,(H,17,18)

InChI key

PUQIRTNPJRFRCZ-UHFFFAOYSA-N

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General description

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid is a metabolite of the selective β-1 blocker drug metoprolol.

Application

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid may be used as an analytical standard for the determination of the analyte in environmental water samples, wastewater samples, and human and animal biological samples by various chromatography techniques.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Screening hundreds of emerging organic pollutants (EOPs) in surface water from the Yangtze River Delta (YRD): occurrence, distribution, ecological risk
Peng Y, et al.
Environmental Pollution (Barking, Essex : 1987), 241, 484-493 (2018)
The
Small Animal Clinical Pharmacology, 241, 484-493 (2011)
Development and Validation of RP-HPLC and an Ecofriendly HPTLC Method for Simultaneous Determination of Felodipine and Metoprolol Succinate, and their Major Metabolites in Human Spiked Plasma
Emam AA, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 809(1), 9-14 (2020)
Investigation of pharmaceuticals and their metabolites in Brazilian hospital wastewater by LC-QTOF MS screening combined with a preliminary exposure and in silico risk assessment
Becker RW, et al.
The Science of the Total Environment, 699, 134218-134218 (2020)
Evaluation of in-situ calibration of Chemcatcher passive samplers for 322 micropollutants in agricultural and urban affected rivers
Moschet C, et al.
Water Research, 71, 306-317 (2015)

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