MilliporeSigma
All Photos(1)

Documents

78769

Supelco

1-Methyl-2-pyrrolidinone

analytical standard

All Photos(1)
Synonym(s):
1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
872-50-4
Molecular Weight:
99.13
Beilstein:
106420
EC Number:
212-828-1
MDL number:
MFCD00003193
PubChem Substance ID:
329768179
NACRES:
NA.24

grade

analytical standard

Quality Level

100

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

Assay

≥99.9% (GC)

autoignition temp.

518 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

9.5 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.47 (lit.)
n20/D 1.470

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
MX1395270458494496
1-Methyl-2-pyrrolidinone analytical standard

Supelco

78769

1-Methyl-2-pyrrolidinone

1-Methyl-2-pyrrolidone Meets ACS Specifications GR ACS

Supelco

MX1395

1-Methyl-2-pyrrolidone

1-Methyl-2-pyrrolidinone suitable for HPLC, ≥99%

Sigma-Aldrich

270458

1-Methyl-2-pyrrolidinone

1-Methyl-2-pyrrolidinone biotech. grade, ≥99.7%

Sigma-Aldrich

494496

1-Methyl-2-pyrrolidinone

assay

≥99.9% (GC)

assay

≥99% (GC)

assay

≥99%

assay

≥99.7%

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

-

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

application(s)

-

application(s)

food and beverages

application(s)

peptide synthesis

format

neat

format

-

format

-

format

-

General description

1-Methyl-2-pyrrolidinone is a polar solvent widely used in organic chemistry and polymer chemistry. On a large scale, it finds applications in the recovery and purification of acetylenes, olefins, and diolefins, gas purification, and aromatics extraction from feedstocks.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Application

1-Methyl-2-pyrrolidinone may be used as an eluent and extraction solvent for the extraction of soluble materials in soil samples using size exclusion chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

195.8 °F - Pensky-Martens closed cup

Flash Point(C)

91 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (Example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 3

1 of 3

N-Methyl-d3-2-pyrrolidinone-d6 98 atom % D

Sigma-Aldrich

615854

N-Methyl-d3-2-pyrrolidinone-d6

1-Methyl-2-pyrrolidone EMPLURA®

Supelco

8.06072

1-Methyl-2-pyrrolidone

1-Methyl-2-pyrrolidone for liquid chromatography LiChrosolv®

Supelco

5.43899

1-Methyl-2-pyrrolidone

Xingxing Gu et al.
Frontiers in chemistry, 8, 149-149 (2020-03-21)
A Typha Angustifolia-like MoS2/carbon nanofiber composite as both a chemically trapping agent and redox conversion catalyst for lithium polysulfides has been successfully synthesized via a simple hydrothermal method. Cycling performance and coulombic efficiency have been improved significantly by applying the
David S Hewings et al.
Journal of medicinal chemistry, 54(19), 6761-6770 (2011-08-20)
Histone-lysine acetylation is a vital chromatin post-translational modification involved in the epigenetic regulation of gene transcription. Bromodomains bind acetylated lysines, acting as readers of the histone-acetylation code. Competitive inhibitors of this interaction have antiproliferative and anti-inflammatory properties. With 57 distinct
K J Brodbeck et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(3), 333-344 (1999-10-21)
The role of solvent properties and bath-side composition on the phase inversion dynamics and in vitro protein release kinetics of polylactic-co-glycolic acid (PLGA) solutions has been examined using dark ground imaging, in vitro release rate, and SEM techniques. Thermodynamic phase
B A Jönsson et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(2), 351-357 (1997-07-04)
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction
Laura Vogelaar et al.
Small (Weinheim an der Bergstrasse, Germany), 1(6), 645-655 (2006-12-29)
Phase separation micromolding (PSmicroM) is a versatile microfabrication technique that can be used to structure a very broad range of polymers, including block copolymers and biodegradable and conductive polymers without the need for clean-room facilities. By incorporating a subsequent process
View All Related Papers

Articles

The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service