78943

Butylated hydroxyanisole

analytical standard

• Synonym(s): Butylated hydroxyanisole, E320, 2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA
• Linear Formula: (CH₃)₃CC₆H₃(OCH₃)OH
• CAS Number: 25013-16-5
• Molecular Weight: 180.24
• EC Number: 246-563-8
• MDL number: MFCD01779059
• E Number: E320
• NACRES: NA.24

Properties

• Quality Level: 100
• grade: analytical standard
• vapor density: 6.2 (vs air)
• Assay: ≥99.0% (sum of isomers, GC)
• autoignition temp.: 599 °F
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 58-60 °C (lit.)
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• InChI: 1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
• InChI key: MRBKEAMVRSLQPH-UHFFFAOYSA-N

Description

General description

Butylated hydroxyanisole (BHA), a lipophilic compound, is reported to exhibit antimicrobial activity against molds and Gram-positive bacteria. It also finds applications as a direct/indirect additive in adhesives, lubricants, food packaging materials, defoaming agents, as a preservative in cosmetic products, antioxidant in petroleum products including jet fuels, cutting oils, rubber latex gloves, paints, lacquers, adhesive hardeners, cleaning agents, thinners, plastics, etc. It is also widely used as an antioxidant in food industry.††

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Application

Butylated hydroxyanisole may be used as an analytical reference standard for the quantification of the analyte in the following:

• Food samples using square-wave voltammetry (SWV), further confirmed by high-performance liquid chromatography technique (HPLC) and capillary electrophoresis (CE) coupled with end-column amperometric detection.
• Cosmetics using fluorescence spectroscopy with second-order calibration, further confirmed by HPLC technique.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302 - H411
• Precautionary Statements: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): 241.9 °F - Pensky-Martens closed cup
• Flash Point(C): 116.6 °C - Pensky-Martens closed cup