81172

Poly(ethylene glycol)

tested according to Ph. Eur., 400

• Synonym(s): Macrogol 400, Polyethylene glycol, PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• NACRES: NA.21
• PubChem Substance ID: 24887676
• UNSPSC Code: 12352104
• MDL number: MFCD00081839

Properties

• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
• agency: tested according to Ph. Eur.
• form: liquid
• mol wt: 380-420
• greener alternative product characteristics: Safer Solvents and Auxiliaries; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• application(s): pharmaceutical (small molecule)
• greener alternative category: Aligned
• Quality Level: 200

Description

General description

Polyethylene glycol (PEG) is a polyether compound[1] with repeated ethylene glycol units[-(CH₂CH₂O)_n].[2]

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used as a liquid medium to prepare shear thickening fluid (STF) by directly mixing it with fumica silica.[3][4][5]

Biochem/physiol Actions

Polyethylene glycol (PEG) is a synthetic polymer[6] and is used as an additive in food, cosmetics, and pharmaceuticals.[1] It is also involved in biomedical applications like biosensing, imaging, and tissue engineering. PEG is used as a gold standard in bioconjugation and nanomedicine thereby increasing blood circulation time and improving drug efficacy. PEG-conjugated drugs are approved by the U.S. Food and Drug Administration (FDA). They are considered safe for use in humans.[6] PEG reduces the liver uptake and repels protein adsorption, which makes it useful in nanocoating.[7]

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves