Selective inhibition of uncoating of echovirus 12 by rhodanine A study on early virus-cell interactions
Eggers, Hans J
Virology, 78(1), 241-252 (1977)
M. Thies et al.
Mikrochimica Acta, 809-809 (1973)
Parminder Singh et al.
Biochemistry, 51(27), 5434-5442 (2012-06-19)
A perturbation of FtsZ assembly dynamics has been shown to inhibit bacterial cytokinesis. In this study, the antibacterial activity of 151 rhodanine compounds was assayed using Bacillus subtilis cells. Of 151 compounds, eight strongly inhibited bacterial proliferation at 2 μM....
Tihomir Tomašić et al.
Expert opinion on drug discovery, 7(7), 549-560 (2012-05-23)
Rhodanine-based compounds have been associated with numerous biological activities. After many years of research in drug discovery, they have gained a reputation as being pan assay interference compounds (PAINS) and frequent hitters in screening campaigns. Rhodanine-based compounds are also aggregators...
Huan-qiu Li et al.
Bioorganic & medicinal chemistry, 20(14), 4194-4200 (2012-06-29)
A series of novel rhodanine-based acylsulfonamide derivatives were designed, synthesized, and evaluated as small-molecule inhibitors of anti-apoptotic Bcl-2 protein. These compounds exhibit potent antiproliferative activity in three human tumor cell lines (Hep G2, PC-3 and B16-F10). Among them, the most...