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85548

Supelco

Span® 80

greener alternative

viscosity 1000-2000 mPa.s (20 °C)

Synonym(s):

Sorbitan monooleate, Span® 80

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About This Item

Empirical Formula (Hill Notation):
C24H44O6
CAS Number:
Molecular Weight:
428.60
Beilstein/REAXYS Number:
8172514
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

form

liquid

mol wt

428.60 g/mol

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.48 (lit.)

viscosity

1000-2000 mPa.s(20 °C)

HLB value

4.3±1.0

density

0.99 g/mL at 20 °C
0.986 g/mL at 25 °C (lit.)

greener alternative category

SMILES string

[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

InChI key

NWGKJDSIEKMTRX-AAZCQSIUSA-N

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General description

Span® 80 is a sorbitan ester series of surfactant. It is produced by esterification of one or more sorbitan hydroxyl group with fatty acid. It is hydrophobic in nature. This non-ionic surfactant can be used to form oil-in-water emulsions and in combination with low HLB surfactants can form water-in-oil emulsions. EPA approved oil spill dispersant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is biodegradable surfactant, thus aligns with "Use of Renewable Feedstocks" and "Design for Degradation" principles of Green Chemistry, and belongs to "12 principles aligned" category of our greener alternatives.

Application

Span® 80 was suitable as surfactant in the preparation of Poly(divinylbenzene) emulsion-derived (PolyHIPE) solid foam. It may be suitable as emulsifier used to extract 24 samples of emulsion explosives with hexane which were analysed using GC-MS.

Legal Information

Span is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Morphology and surface area of emulsion-derived (PolyHIPE) solid foams prepared with oil-phase soluble porogenic solvents: Span 80 as surfactant.
Barbetta, Andrea, and Neil R. Cameron
Macromolecules, 37, 3188-3201 (2004)
Fei-Fei Tian et al.
Journal of chromatography. A, 1218(22), 3521-3528 (2011-04-19)
A novel approach for identification and determination of emulsion explosives with Span-80 (sorbitol mono-oleate) as the emulsifier and their postblast residues by gas chromatography-mass spectrometry (GC-MS) has been developed. 24 kinds of emulsion explosives collected have been processed by transesterification
Michael E. Aulton, Kevin M.G. Taylor
Aulton's Pharmaceutics: The Design and Manufacture of Medicines, 445-445 (2013)
Geneviève LeBel et al.
Applied and environmental microbiology, 80(17), 5484-5492 (2014-06-29)
Streptococcus suis serotype 2 is known to cause severe infections (meningitis, endocarditis, and septicemia) in pigs and is considered an emerging zoonotic agent. Antibiotics have long been used in the swine industry for disease treatment/prevention and growth promoters. This pattern
Hoang Hirschberg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7 (2012-02-15)
In the search for an optimal approach for the transcutaneous immunization (TCI) of hepatitis B surface antigen (HBsAg), two vesicle formulations, L595 vesicles (composed of sucrose-laurate ester and octaoxyethylene-laurate ester) and sPC vesicles (composed of soybean-phosphatidylcholine and Span-80) were prepared

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