Tetrahexylammonium bromide

suitable for ion pair chromatography, LiChropur, ≥99.0% (AT)

Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level




≥99.0% (AT)




ion pair chromatography: suitable


99-100 °C (lit.)


10 % in methanol

UV absorption

λ: 240 nm Amax: 0.06
λ: 250 nm Amax: 0.04
λ: 260 nm Amax: 0.03
λ: 500 nm Amax: 0.03


corresponds to standard for filter test

SMILES string




InChI key


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General description

The utilization of ion-pairing reagents as mobile phase additives allows the elution of ionic and highly polar substances using reversed phase HPLC columns. The purity of mobile phase additives is a prime factor to their successful application. Sigma-Aldrich offers an outstanding collection of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) analyzes. All mobile phase additives are rigorously tested with special emphasis on the requirements of modern reversed phase HPLC:

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes


Risk Statement


Safety Statement



NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Y Uyama et al.
Pflugers Archiv : European journal of physiology, 426(5), 363-370 (1994-03-01)
Effects of tetraalkylammonium ions, having tetraalkyl chains of increasing length from ethyl to octyl, on inositol-trisphosphate (InsP3)-induced Ca2+ release and contractile mechanics were examined in guinea-pig skinned ileal smooth muscle longitudinal strips. Although tetrahexylammonium ions (THexA) appeared to be the...
L G Sayers et al.
Biochimica et biophysica acta, 1152(1), 177-183 (1993-10-10)
In this study we show that the potassium-channel blocker tetrahexyl ammonium chloride (THA+) is able to inhibit inositol 1,4,5-trisphosphate (InsP3)-induced calcium release in an apparently biphasic fashion with a IC50 of 3 microM. This inhibition was not alleviated by valinomycin...
A F Hofmann
Journal of lipid research, 8(1), 55-58 (1967-01-01)
Ethyl acetate or chloroform solutions of tetraheptylammonium chloride, an oil-soluble quaternary amine, quantitatively extract polar, anionic lipids such as steroid or bile salt conjugates from aqueous solution by a process of anion exchange.
L Zhang et al.
The Journal of pharmacology and experimental therapeutics, 288(3), 1192-1198 (1999-02-23)
Polyspecific organic cation transporters in epithelia play an important role in the elimination of many endogenous bioactive amines and therapeutically important drugs. Recently, the first human organic cation transporter (hOCT1) was cloned from liver. The purpose of the current study...
K M Sunasara et al.
Biotechnology progress, 17(5), 897-906 (2001-10-06)
This work investigates the utility of RPLC displacement chromatography for the purification of recombinant brain derived neurotrophic factor (rHu-BDNF) from its variants and E. coli. protein (ECP) impurities. The closely associated variants (six in total) differ by one amino acid...

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