87920

Supelco

Tetramethylsilane

analytical standard, for NMR spectroscopy, ACS reagent

Linear Formula:
Si(CH3)4
CAS Number:
Molecular Weight:
88.22
Beilstein/REAXYS Number:
1696908
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

ACS reagent
analytical standard
for NMR spectroscopy

vapor pressure

11.66 psi ( 20 °C)

assay

≥99.5% (GC)

form

liquid

CofA

certificate is enclosed in each package

autoignition temp.

842 °F

refractive index

n20/D 1.358 (lit.)
n20/D 1.359

bp

26-28 °C (lit.)

mp

−99 °C (lit.)

density

0.648 g/mL at 25 °C (lit.)

Featured Industry

Environmental

format

neat

storage temp.

2-8°C

SMILES string

CSi(C)(C)C

InChI

1S/C4H12Si/c1-5(2,3)4/h1-4H3

InChI key

CZDYPVPMEAXLPK-UHFFFAOYSA-N

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General description

Tetramethylsilane has been recommended by the International Union of Pure and Applied Chemistry (IUPAC) as a universal reference for all nuclides. It is commonly used as a reference standard in nuclear magnetic resonance (NMR) for measuring proton chemical shifts and the temperature dependence of the 1H chemical shift of TMS in solvents such as chloroform, methanol, and dimethylsulfoxide is studied.

Application

Tetramethylsilane may be used as an internal standard for the quantitative analysis of medicinal plant extracts and herbal products using the quantitative NMR (qNMR) method. It may also be used as an internal standard to investigate peroxide-based chemical systems for the crosslinking reactions carried on isotactic polypropylene using FT-IR spectrometry and proton nuclear magnetic resonance (1H NMR) techniques.

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

F+

Risk Statement

12

Safety Statement

3/7-16-33-45

RIDADR

UN 2749 3 / PGI

WGK Germany

WGK 3

Flash Point(F)

-16.6 °F - closed cup

Flash Point(C)

-27 °C - closed cup

Temperature dependence of the 1H chemical shift of tetramethylsilane in chloroform, methanol, and dimethylsulfoxide
Hoffman ER, et al.
Journal of Magnetic Resonance, 176(1), 87-98 (2005)
Monitoring the chemical crosslinking of propylene polymers through rheology
Romani F, et al.
Polymer, 43(4), 1115-1131 (2002)
August Andersson et al.
FEBS letters, 545(2-3), 139-143 (2003-06-14)
The interaction between the peptide hormone motilin and bicelles has been investigated by pulsed field gradient-nuclear magnetic resonance methods and by the use of paramagnetic probes. Diffusion coefficients were measured for motilin, the phospholipids with and without motilin, and for...
Siddheshwar K Chauthe et al.
Phytochemical analysis : PCA, 23(6), 689-696 (2012-06-19)
Quantitative analysis and standardisation of plant extracts or herbal products is a tedious process requiring time-consuming sample preparation and analytical method development for the resolution of analyte peaks from the complex natural extract. Quantitative analysis by HPLC requires a pure...
Roy E Hoffman
Journal of magnetic resonance (San Diego, Calif. : 1997), 163(2), 325-331 (2003-08-14)
The chemical shift of TMS is commonly assumed to be zero. However, it varies by over 1 ppm for 1H and 4 ppm for 13C and shows a correlation with the physical properties of the solvent. Using the commonly accepted...

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