90984

Sucralose

analytical standard

• Synonym(s): 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose
• Empirical Formula (Hill Notation): C₁₂H₁₉Cl₃O₈
• CAS Number: 56038-13-2
• Molecular Weight: 397.63
• NACRES: NA.24
• E Number: E955
• PubChem Substance ID: 329769983
• UNSPSC Code: 85151701
• EC Number: 259-952-2
• MDL number: MFCD03648615
• Beilstein/REAXYS Number: 3654410

Properties

• InChI: 1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
• InChI key: BAQAVOSOZGMPRM-QBMZZYIRSA-N
• SMILES string: OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl
• grade: analytical standard
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• Quality Level: 100

Description

General description

Sucralose is a derivative of sucrose[1], which is generally used as a non-nutritive sweetener in foods and beverages.[2]

Sucralose, belonging to the class of synthetic sweeteners,[3] is a noncarcinogenic taste enhancer, found to be 400-800 times sweeter than sucrose. It is not involved in inducing glycemic response and is virtually noncaloric.[4] Sucralose is used as a part of a comprehensive portfolio of analytical standards to monitor natural and artificial sugar substitutes in the food and beverage industries. This product finds applications as a sweetener in a variety of food products and beverages including desserts, bakery products, canned fruits/vegetables, dressings, breakfast cereals, confectionery, medical foods, dietary supplements, etc.[4][3]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sucralose may be used as an analytical reference standard for the quantification of the analyte in:

• Commercial sugar-free products such as Splenda and Red Raspberry Diet Rite beverage using high performance anion-exchange (HPAE) chromatography coupled with pulsed amperometric detection (PAD).[4]
• Water and beverage samples using liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS).[5]

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable