MilliporeSigma
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91719

Supelco

Trifluoroacetic anhydride

for GC derivatization, LiChropur, ≥99.0% (GC)

Synonym(s):
TFAA
Linear Formula:
(CF3CO)2O
CAS Number:
Molecular Weight:
210.03
Beilstein:
746197
EC Number:
MDL number:
PubChem Substance ID:

grade

for GC derivatization

Quality Level

vapor pressure

6.28 psi ( 20 °C)

Assay

≥99.0% (GC)

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

reagent type: derivatization reagent
reaction type: Esterifications

technique(s)

gas chromatography (GC): suitable (ECD)

refractive index

n20/D 1.3 (lit.)

bp

39.5-40 °C (lit.)

mp

−65 °C (lit.)

density

1.511 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

InChI key

QAEDZJGFFMLHHQ-UHFFFAOYSA-N

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This Item
9170780457DX0837
Trifluoroacetic anhydride for GC derivatization, LiChropur™, ≥99.0% (GC)

Supelco

91719

Trifluoroacetic anhydride

Trifluoroacetic acid puriss. p.a., suitable for HPLC, ≥99.0% (GC)

Sigma-Aldrich

91707

Trifluoroacetic acid

Trifluoroacetic acid eluent additive for LC-MS, LiChropur™, ≥99.0% (GC)

Supelco

80457

Trifluoroacetic acid

Dichloromethane OmniSolv® HR-GC

Supelco

DX0837

Dichloromethane

vapor pressure

6.28 psi ( 20 °C)

vapor pressure

97.5 mmHg ( 20 °C)

vapor pressure

97.5 mmHg ( 20 °C)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

assay

≥99.0% (GC)

assay

≥99.0% (GC)

assay

≥99.0% (GC)

assay

≥99.9% (GC)

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

gas chromatography (GC): suitable (ECD)

technique(s)

HPLC: suitable, LC/MS: suitable

technique(s)

LC/MS: suitable

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.3 (lit.)

refractive index

n20/D 1.3 (lit.)

refractive index

n20/D 1.3 (lit.)

refractive index

n20/D 1.424 (lit.)

Application

Learn more in the Product Information
Suitable for derivatization of amines, aryl amines, phenolic amines, primany amines, tertiary aromatic amines, amino acids, aminoalkylphosphoric acids, 2-aminoethylphosphoric acid, 1-hydroxy-2-aminoethylphosponic acid, amphetamine, beta blocker drugs, creatinine, desipramine, dopamine, glutathione, glycol (MOPEG), guanidine drugs, histidine, n-hydroxy-2-fluorenylacetamide, n-hydroxylamines, hydroxy acids, p-hydroxyamphetamine, 4-hydroxycoumarins, p-hydroxynorephedrine, hydroxysteroids, 5-hydroxytryptamine, indoles, Iodoamino acids, carbaryl and hydroxylated metabolites, metanephrine, methylphenidate, norepinephrine, normetanephrine, peptide amide, phenformin, phenols, phentermine, phenylthiohydantoin amino acid, propranolol, sulfonamides, sulfonylureas, thiamine, vanillymandelic acid, trisubstituted ureas and urea.

Other Notes

For the protection of prim. and sec. amines; derivatives are more volatile
Reagent for cabethoxy, butyl ester, n-methyl, methyl ester, di(trifluoroacetyl), hexafluoroisopropyl ester, acetyl or trifluoroacetyl phenylthihydantoins, trifluoroacetyl (2-hydroxy-2-methyl)ethyl, n-trifluoroacetyl, trifluoroacetyl (TFA), trifluoroacetamide, 4-trifluoromethyl-2, 6-diamino-1,3,5-triazineacetyl and trifluoroacetyl vanillin.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Supplementary Hazards

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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