You will contribute to create a sustainable world, significantly lowering environmental impact. Biorenewable solvents also decrease petroleum sources dependency, have higher recovery rates, and/or are safer for handling and disposal.
920207
Cyrene™ γ-Valerolactone Blend
BioRenewable, DMF and NMP Substitute
Synonym(s):
γ-Valerolactone Cyrene™ solution, γ-Valerolactone solution, Cyrene solution, Cyrene™ γ-valerolactone solution, GVL Blend
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 mL | Available to ship TODAYfromMILWAUKEE | $149.00 | |
| 1 L | Check Cart for Availability | $269.00 |
About This Item
Empirical Formula (Hill Notation):
C6H8O3
Molecular Weight:
128.13
NACRES:
NA.07
UNSPSC Code:
12191502
form
liquid
greener alternative product characteristics
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
renewable carbon content
100%
density
1.141 g/mL
greener alternative category
General description
Cyrene™ γ-Valerolactone Blend is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.
This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor γ-Valerolactone have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor γ-Valerolactone have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is BioRenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.
Application
This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:
- HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions
- Suzuki-Miyaura coupling reaction.
- Sonogashira coupling reaction.
- Reductive homocoupling reaction.
Features and Benefits
- Independently certified as 100% renewable carbon.
- Closer physical properties of NMP and DMF while maintaining high reaction yields.
- Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
- Both Cyrene and GVL are also much safer for handling without the genotoxic concerns of other solvents.
- It has a lower viscosity than neat Cyrene making it more optimized for automated processes.
Legal Information
CYRENE is a trademark of Circa Group Pvt Ltd
1 of 1
This Item | |||
|---|---|---|---|
| form liquid | form liquid | form liquid | form liquid |
| density 1.141 g/mL | density 1.153 g/mL | density 1.05 g/mL at 25 °C (lit.) | density 0.884 g/mL at 25 °C |
| greener alternative category | greener alternative category , Aligned | greener alternative category | greener alternative category |
| greener alternative product characteristics Safer Solvents and Auxiliaries | greener alternative product characteristics Safer Solvents and Auxiliaries | greener alternative product characteristics Safer Solvents and Auxiliaries | greener alternative product characteristics Safer Solvents and Auxiliaries |
| renewable carbon content 100% | renewable carbon content 100% | renewable carbon content - | renewable carbon content - |
| sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability Greener Alternative Product |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 1
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Cyrene? blends: a greener solvent system for organic syntheses
Sullivan C, et al.
Green Chemistry, 24, 7184-7193 (2022)
Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene?(dihydrolevoglucosenone)
Webb DA, et al.
RSC Sustainability, 1, 1522-1529 (2023)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 920207-100ML | 04065266442748 |
| 920207-1L | 04065266442755 |
-
Why should you use BioRenewable solvents?
1 answer-
Helpful?
-
-
Do BioRenewable solvents have a similar quality to petroleum-based solvents?
1 answer-
BioRenewable solvents can have the same or higher purity level compared to traditional solvents. These solvents are free of the many byproducts of petroleum manufacturing, such as benzene, aldehydes, and ethers.
Helpful?
-
-
What is a BioRenewable solvent?
1 answer-
BioRenewable solvents are sourced from renewable and sustainable biobased materials, such as soy/palm oil, wood waste, hay or corn byproducts, etc. It is important to highlight that our BioRenewable products do not compete with food production.
Helpful?
-