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92264

Supelco

4-Methoxyphenol

analytical standard

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Synonym(s):
4-Hydroxyanisole, 4-MP, HQMME, Hydroquinone monomethyl ether, MEHQ, MQ-F, p-Guaiacol
Linear Formula:
CH3OC6H4OH
CAS Number:
Molecular Weight:
124.14
Beilstein:
507924
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

4.3 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

Assay

≥98.5% (GC)

autoignition temp.

789 °F

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

bp

243 °C (lit.)

mp

55-57 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

COc1ccc(O)cc1

InChI

1S/C7H8O2/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3

InChI key

NWVVVBRKAWDGAB-UHFFFAOYSA-N

Gene Information

human ... TYR(7299)

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1 of 4

This Item
54050M18655PHR2473
4-Methoxyphenol analytical standard

Supelco

92264

4-Methoxyphenol

4-Methoxyphenol purum, &#8805;98.0% (HPLC)

Sigma-Aldrich

54050

4-Methoxyphenol

4-Methoxyphenol ReagentPlus&#174;, 99%

Sigma-Aldrich

M18655

4-Methoxyphenol

Supelco

Supelco

PHR2473

Guaiacol Impurity G

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

application(s)

-

application(s)

-

application(s)

pharmaceutical

format

neat

format

-

format

-

format

-

vapor density

4.3 (vs air)

vapor density

4.3 (vs air)

vapor density

4.3 (vs air)

vapor density

-

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

<0.01 mmHg ( 20 °C)

vapor pressure

-

General description

4-Methoxyphenol belongs to the class of hydroquinone (HQ) derivatives. It is widely used as a skin whitening agent, because it can exert hypo-pigmenting effects. It also finds applications as a stabilizer for chlorinated hydrocarbons, ethyl cellulose, UV (ultraviolet) inhibitor, inhibitor for acrylic monomers, etc.

Application

4-Methoxyphenol may be used as an analytical reference standard for the quantification of the analyte in cosmetic products using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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T1503
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25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Experimental and statistical validation of HPLC analysis of hydroquinone and its 4-methoxyphenol, 4-ethoxyphenol and 4-benzyloxyphenol ethers in cosmetic products
Borremans M, et al.
Chromatographia, 50(5-6), 346-352 (1999)
Proctor and Hughes' Chemical Hazards of the Workplace, 50(5-6), 346-352 (2004)
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)
Travis M Doggett et al.
Alcoholism, clinical and experimental research, 38(9), 2414-2426 (2014-09-27)
Alcohol intoxication can increase inflammation and worsen injury, yet the mechanisms involved are not clear. We investigated whether acute alcohol intoxication increases microvascular permeability and investigated potential signaling mechanisms in endothelial cells that may be involved. Conscious rats received a
Chongming Liu et al.
Journal of mass spectrometry : JMS, 49(8), 692-699 (2014-07-22)
On contrary to the widely accepted conviction that the m/z 93 ion derived from phenol does not react with CO2, we demonstrate that it makes an adduct with CO2 to a small but demonstrable extent. For example, the product-ion mass

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