92301

Millipore

Listeria mono Selective Supplement I

suitable for microbiology

Synonym(s):
Polymyxin B sulfate salt, Listeria monocytogenes Selective Supplement I
Empirical Formula (Hill Notation):
C55H96N16O13 · 2H2SO4
CAS Number:
Molecular Weight:
1385.61
EC Number:
MDL number:
NACRES:
NA.85
Pricing and availability is not currently available.

Quality Level

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

microbiology: suitable

Featured Industry

Environmental
Food and Beverages

Mode of action

cell membrane | interferes

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi

storage temp.

2-8°C

suitability

Listeria spp.

InChI

1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

InChI key

HNDFYNOVSOOGDU-UHFFFAOYSA-N

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Related Categories

General description

Chemical structure: peptide
A selective supplement recommended by ISO Committee for the isolation of Listeria species.

Application

for the isolation of Listeria species

Biochem/physiol Actions

Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides†, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.

Antimicrobial spectrum: Has bactericidal action on most gram-negative bacilli††, including E. Coli and on most fungi and gram-positive bacteria.

Components

(per vial, sufficient for 500 ml medium)
Polymyxin B sulphate 38350 IU

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Lee Sun New et al.
Analytical and bioanalytical chemistry, 405(4), 1407-1415 (2012-11-28)
With increasing multidrug resistance coupled to a poor development pipeline, clinicians are exploring antimicrobial combinations to improve treatment outcomes. In vitro hollow-fiber infection model (HFIM) is employed to simulate human in vivo drug clearance and investigate pharmacodynamic synergism of antibiotics....
Conjugated polymer-coated bacteria for multimodal intracellular and extracellular anticancer activity.
Chunlei Zhu et al.
Advanced materials (Deerfield Beach, Fla.), 25(8), 1203-1208 (2013-01-03)
Kensuke Nakamura et al.
The American journal of emergency medicine, 31(5), 893-893 (2013-02-13)
Septic patients often have low cardiac output. Some of them present severe cardiac dysfunction such as septic cardiomyopathy. However, no well-known and effective treatment for septic cardiomyopathy exists. The effect of endotoxin adsorption by polymyxin B–immobilized fiber column–direct hemoperfusion (PMX-DHP)...
A Bonura et al.
Allergy, 68(3), 297-303 (2013-01-22)
The major allergens in Parietaria pollen, Par j 1 and Par j 2, have been identified as lipid transfer proteins. The family of the Par j 1 allergens is composed of two isoforms, which differ by the presence of a...
The novel polymyxin derivative NAB739 is remarkably less cytotoxic than polymyxin B and colistin to human kidney proximal tubular cells.
Martti Vaara et al.
International journal of antimicrobial agents, 41(3), 292-293 (2012-11-28)
Protocols
In recent years it has been recognized that Listeria is an important public health problem. The disease affects primarily people of advanced age, pregnant women, newborns, and adults with weakened immune systems.
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