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MilliporeSigma

92574

Mefenamic acid

analytical standard

Synonym(s):

2-[(2,3-Dimethylphenyl)amino]benzoic acid, N-(2,3-Xylyl)anthranilic acid

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250 MG

$91.30

$91.30

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About This Item

Empirical Formula (Hill Notation):
C15H15NO2
CAS Number:
61-68-7
Molecular Weight:
241.29
NACRES:
NA.24
PubChem Substance ID:
329770141
UNSPSC Code:
41116107
EC Number:
200-513-1
MDL number:
MFCD00051721

Key Documents

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InChI key

HYYBABOKPJLUIN-UHFFFAOYSA-N

InChI

1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)

SMILES string

Cc1cccc(Nc2ccccc2C(O)=O)c1C

grade

analytical standard

assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤1.0% water

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

grade

analytical standard

grade

analytical standard

grade

analytical standard

grade

analytical standard, for drug analysis

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

assay

≥98.5% (HPLC)

assay

-

assay

≥98.0% (HPLC)

assay

≥97% (HPLC)

format

neat

format

neat

format

neat

format

neat

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

-

Application

An NSAID. Circumvents MRP-mediated multidrug resistance. Specifically and significantly potentiates the cytotoxicity of anthracyclines as well as teniposide, VP-16 and vincristine.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1472
BCCK0387
BCCG7671
BCCD0183
BCBW8340

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Renata Colombo et al.
Journal of environmental management, 167, 206-213 (2015-12-22)
Mefenamic acid (MEF) is a non-steroidal anti-inflammatory drug indicated for relief of mild to moderate pain, and for the treatment of primary dysmenorrhea. The presence of MEF in raw and sewage waters has been detected worldwide at concentrations exceeding the
Umang V Shah et al.
International journal of pharmaceutics, 472(1-2), 140-147 (2014-06-15)
The role of surface properties, influenced by particle processing, in particle-particle interactions (powder cohesion) is investigated in this study. Wetting behaviour of mefenamic acid was found to be anisotropic by sessile drop contact angle measurements on macroscopic (>1cm) single crystals
Rachel Moll et al.
The Cochrane database of systematic reviews, (3)(3), CD007553-CD007553 (2011-03-18)
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). It is most often used for treating pain of dysmenorrhoea in the short term (seven days or less), as well as mild to moderate pain including headache, dental pain, postoperative and postpartum
Harini Venkataraman et al.
Bioorganic & medicinal chemistry, 22(20), 5613-5620 (2014-07-08)
Cytochrome P450 BM3 mutants are promising biocatalysts for the production of drug metabolites. In the present study, the ability of cytochrome P450 BM3 mutants to produce oxidative metabolites of structurally related NSAIDs meclofenamic acid, mefenamic acid and tolfenamic acid was
C Reichert et al.
Clinical toxicology (Philadelphia, Pa.), 52(6), 629-634 (2014-05-23)
Seizures during intoxications with pharmaceuticals are a well-known complication. However, only a few studies report on drugs commonly involved and calculate the seizure potential of these drugs. To identify the pharmaceutical drugs most commonly associated with seizures after single-agent overdose
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