MilliporeSigma
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93440

Supelco

Trizma® base

certified reference material for titrimetry, certified by BAM, ≥99.5%

Synonym(s):
2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

description

aminopeptidase substrate

Assay

≥99.5%

quality

certified by BAM

technique(s)

titration: suitable

pH

10.5-12

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: soluble (678 g/l at 20 °C)

format

neat

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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General description

Trizma® base is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content is determined by volumetric neutralization titration using a combined pH glass electrode. The certified value and uncertainty measurement of the standard are in accordance with ISO Guide 35.

Application

It finds its use as a certified reference material (CRM) for the standardization of volumetric solutions in acidimetric titrations.

Features and Benefits

  • Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • High-purity material traceable to NIST SRM
  • High-quality offering accurate titer determinations
  • Accompanied by a certificate of analysis (CoA)

Analysis Note

Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.

Other Notes

The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Legal Information

Trizma is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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