93893

Supelco

Physcion

analytical standard

Synonym(s):
1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, Parietin, Rheochrysidin, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether
Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
Molecular Weight:
284.26
Beilstein/REAXYS Number:
6770499
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

assay

≥98.0% (HPLC)

form

neat

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Food and Beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

InChI key

FFWOKTFYGVYKIR-UHFFFAOYSA-N

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General description

Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Physcion may be used as an analytical reference standard for the quantification of the analyte in medicinal plants, pharmaceutical preparations, vegetables, herbs and liquors using different chromatography techniques.

Biochem/physiol Actions

Anthraquinone-derivative found in medicinal herbs.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants
Mueller O.S, et al.
Food And Chemical Toxicology, 37(5), 481-491 (1999)
Zhenli Liu et al.
Planta medica, 77(16), 1855-1860 (2011-06-16)
The dried roots of Polygonum multiflorum Thunb. (Heshouwu) and their processed products (Zhi-heshouwu) are widely used in traditional Chinese medicine, yet their therapeutic effects are different. Previous investigations focused mainly on the differences between Heshouwu and Zhi-heshouwu in the contents...
Henning Hopf et al.
Acta crystallographica. Section C, Crystal structure communications, 68(Pt 8), o317-o319 (2012-08-02)
The structure of the title compound, 7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione, C(16)H(12)O(5), was originally reported by Ulický et al. [Acta Cryst. (1991). C47, 1879-1881] in the space group P2(1)2(1)2(1) [polymorph (Io)]. The new polymorph, (Im), crystallizes in the space group P2(1)/c. The molecular structures...
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica...
Simultaneous determination of five anthraquinones in medicinal plants and pharmaceutical preparations by HPLC with fluorescence detection
He D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 49(4), 1123-1127 (2009)

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