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S0817

Sigma-Aldrich

Sodium chloride solution

0.85%

Linear Formula:
NaCl
CAS Number:
Molecular Weight:
58.44
Beilstein:
3534976
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

concentration

0.83-0.86% NaCl
0.85%

density

1.000 g/cm3 at 20 °C

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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General description

Sodium chloride is commonly referred to as “salt” and is naturally present as mineral halite. Sodium chloride solution is highly used in chemical production.

Application

Sodium chloride solution has been used in the preparation of neurotoxin 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) stock solution.

Biochem/physiol Actions

Sodium chloride solution is applicable in protein crystallization. It favours better protein-protein interactions.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

A model of MPTP-induced Parkinson's disease in the goldfish
Weinreb O and Youdim MB
Nature Protocols, 2(11) (2007)
Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte.
Curtis RA, et al.
Biophysical Chemistry, 98(3), 249-265 (2002)
Sodium Chloride
Kirk-Othmer Encyclopedia of Chemical Technology, 1-27 (2000)
Guus M Bol et al.
EMBO molecular medicine, 7(5), 648-669 (2015-03-31)
Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including lung cancer
Justin W Leung et al.
PLoS genetics, 10(3), e1004178-e1004178 (2014-03-08)
Histone ubiquitinations are critical for the activation of the DNA damage response (DDR). In particular, RNF168 and RING1B/BMI1 function in the DDR by ubiquitinating H2A/H2AX on Lys-13/15 and Lys-118/119, respectively. However, it remains to be defined how the ubiquitin pathway

Protocols

Protein Determination Modified Lowry Method

To standardize a procedure for the determination of protein by modified Lowry.

Enzymatic Assay of Deoxyribonuclease I (EC 3.1.21.1)

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

Enzymatic Assay of Aprotinin

Objective: To standardize a procedure for the enzymatic assay of Aprotinin.

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