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A1028

Sigma-Aldrich

8-Anilino-1-naphthalenesulfonic acid

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Synonym(s):
N-Phenyl peri acid, ANS, ANSA
Linear Formula:
C6H5NHC10H6SO3H
CAS Number:
Molecular Weight:
299.34
Beilstein:
1843887
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Assay

≥97% (HPLC)

Quality Level

form

powder

mp

215-217 °C (dec.) (lit.)

solubility

DMF: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12

InChI

1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)

InChI key

FWEOQOXTVHGIFQ-UHFFFAOYSA-N

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1 of 4

This Item
D464510417H1252
Homovanillic acid Fluorimetric reagent

Sigma-Aldrich

H1252

Homovanillic acid

form

powder

form

powder

form

solid

form

powder

mp

215-217 °C (dec.) (lit.)

mp

>300 °C

mp

245-253 °C

mp

142-145 °C (lit.)

solubility

DMF: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 0.1 g/5mL, clear to very slightly hazy (hot), NaOH: 1 N, H2O: soluble, acetone: soluble, methanol: soluble

solubility

ethanol: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

room temp

Application

8-Anilino-1-naphthalenesulfonic acid (ANS) has been used to study the thermal aggregation of BSA (bovine serum albumin).

Biochem/physiol Actions

8-Anilino-1-naphthalenesulfonic acid (ANS) is an important dye which is used to study the intermediate states in the folding/unfolding pathways of proteins. It is also useful to check the conformational changes involved with the aggregation of proteins. ANS is nonfluorescent in the aqueous solution, however, it fluoresces strongly upon binding to BSA (bovine serum albumin) and denatured proteins. It is used for the detection of albumin in the serum. ANS mainly interacts with the solvent exposed nonpolar (hydrophobic) sites.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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