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A4382

4-Aminoantipyrine

reagent grade

Synonym(s):

4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone

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10 G

$61.40

25 G

$67.90

50 G

$79.20

100 G

$110.00

250 G

$210.00

$61.40

Estimated to ship onMarch 09, 2026Details

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About This Item

Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
83-07-8
Molecular Weight:
203.24
UNSPSC Code:
51384603
NACRES:
NA.31
PubChem Substance ID:
24890855
EC Number:
201-452-3
Beilstein/REAXYS Number:
181635
MDL number:
MFCD00003145

Key Documents

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InChI key

RLFWWDJHLFCNIJ-UHFFFAOYSA-N

InChI

1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3

SMILES string

CN1N(c2ccccc2)C(=O)C(N)=C1C

grade

reagent grade

assay

≥97% (HPLC)

form

powder

Quality Level

300

mp

105-110 °C (lit.)

solubility

water: 50 mg/mL

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1 of 4

This Item
33528D801543827
4-Aminoantipyrine reagent grade

Sigma-Aldrich

A4382

4-Aminoantipyrine

4-Aminoantipyrine puriss. p.a., reag. Ph. Eur., ≥99%

Sigma-Aldrich

33528

4-Aminoantipyrine

4-Dimethylaminoantipyrine reactive nitrogen species scavenger

Sigma-Aldrich

D8015

4-Dimethylaminoantipyrine

4-Aminoantipyrine analytical standard

Supelco

43827

4-Aminoantipyrine

assay

≥97% (HPLC)

assay

≥99%

assay

-

assay

≥99.0% (HPLC)

grade

reagent grade

grade

-

grade

-

grade

analytical standard

solubility

water: 50 mg/mL

solubility

-

solubility

-

solubility

-

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

-

form

solid

form

-

mp

105-110 °C (lit.)

mp

105-110 °C (lit.), 107-109 °C

mp

107-109 °C (lit.)

mp

105-110 °C (lit.)

Application

Reagent for glucose determination in the presence of phenol and peroxidase.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000514389
0000522093
0000522094
0000522094
0000522093

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A Z El-Sonbati et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 213-221 (2012-12-27)
A novel series of copper(II) and palladium(II) with 4-derivatives benzaldehyde pyrazolone (L(n)) were synthesized. The mixed ligand complexes were prepared by using 1,10-phenanthroline (Phen) as second ligand. The structure of these complexes was identified and confirm by elemental analysis, molar
Yue Teng et al.
Journal of hazardous materials, 190(1-3), 574-581 (2011-04-19)
4-Aminoantipyrine (AAP) is widely used in the pharmaceutical industry, in biochemical experiments and in environmental monitoring. AAP as an aromatic pollutant in the environment poses a great threat to human health. To evaluate the toxicity of AAP at the protein
N Raman et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 85(1), 223-234 (2011-10-25)
Few novel 4-aminoantipyrine derived Schiff bases and their metal complexes were synthesized and characterized. Their structural features and other properties were deduced from the elemental analysis, magnetic susceptibility and molar conductivity as well as from mass, IR, UV-vis, (1)H NMR
Isela Lavilla et al.
Talanta, 98, 197-202 (2012-09-04)
In this work, a new method based on the combination of dispersive liquid-liquid microextraction (DLLME) with microvolume spectrophotometry has been developed as a greener and miniaturized alternative to the 5530 APHA standard method for determining phenols in water and wastewater.
Yue Teng et al.
Journal of hazardous materials, 192(3), 1766-1771 (2011-07-26)
The effects of 4-aminoantipyrine (AAP) on oxidative stress induced by glutathione (GSH) depletion in single human erythrocytes were investigated using microfluidic technique and fluorescence imaging. Most cell-based toxicity evaluations on GSH are performed with bulk experiments based on analysis of
View All Related Papers

Protocols

Enzymatic Assay of Lipase Type XIII from Pseudomonas sp. Using a Coupled Enzyme System of Glycerol Kinase and Glycerophosphate Oxidase (EC 3.1.1.3)

Enzymatic assay of lipase type XIII from Pseudomonas sp. using a coupled enzyme system of glycerol kinase and glycerophosphate oxidase (EC 3.1.1.3)

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the recommended storage method for stock solutions of item A4382, 4-Aminoantipyrine?

    1 answer

    1. To enhance solubility, it is advised to warm the tube at 37 ℃ and subsequently shake it in an ultrasonic bath for a brief period. Stock solutions can be stored at temperatures below -20℃ for several months. Ideally, it is recommended to prepare and utilize the solution on the same day. However, if advance preparation is necessary, stock solutions must be sealed and stored below -20℃. Prior to use, allowing the vial to reach room temperature for at least an hour is recommended.

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