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A5131

L-Arginine monohydrochloride

≥98% (HPLC)

Synonym(s):

(S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
210.66
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
214-275-1
MDL number:
Beilstein/REAXYS Number:
3631658

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Product Name

L-Arginine monohydrochloride, reagent grade, ≥98% (HPLC), powder

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

grade

reagent grade

assay

≥98% (HPLC)

form

powder

color

white

mp

>235 °C

solubility

H2O: 50 mg/mL

application(s)

cell analysis

Quality Level

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1 of 4

This Item
A6969905381.01544
grade

reagent grade

grade

-

grade

certified reference material, TraceCERT®

grade

-

form

powder

form

powder

form

-

form

solid

assay

≥98% (HPLC)

assay

98.5-101.0%

assay

-

assay

98.5-101.0% dry basis (perchloric acid titration)

color

white

color

white

color

white

color

-

solubility

H2O: 50 mg/mL

solubility

water: 100 mg/mL, clear, colorless

solubility

-

solubility

water: 730 g/L at 20 °C

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

500

Application

L-Arginine monohydrochloride has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster. It has also been used to develop a non-invasive chronic pancreatitis model of rat.[1][2]

Biochem/physiol Actions

L-Arginine is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.[3]
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
Yang Liu et al.
Biochemical and biophysical research communications, 525(3), 620-625 (2020-03-03)
The circadian clock, a biochemical oscillator, plays a fundamental role in health and diseases. Ferroptosis, a type of regulated cell death driven by oxidative stress, is a prominent feature in iron-induced tissue injury. However, whether an impaired circadian clock contributes
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)
Enyong Dai et al.
Nature communications, 11(1), 6339-6339 (2020-12-15)
Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or depletion of Gpx4, an antioxidant enzyme reported as an important ferroptosis suppressor, in the pancreas

Articles

Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.

Questions

1–7 of 7 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Ho bisogno di l-arginina cloridrato ≥98,5 % soluzione per via endovenosa, è disponibile?

    1 answer
    1. This product is listed for research use only and is not suitable for human or animal use. There are no products available for intravenous use in any form.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. What are the solubility properties of L-Arginine monohydrochloride (Product No. A5131)?

    1 answer
    1. L-Arginine monohydrochloride is soluble in water at a concentration of 1M (210 mg/mL).

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  6. What is the method of preparation process for the A5131 L-Arginine monohydrochloride?

    1 answer
    1. No animal proteins or products are used in the fermentation process or purification of the L-Arginine.

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  7. Are solutions of Product No. A5131 (L-Arginine monohydrochloride) autoclavable?

    1 answer
    1. Arginine is routinely autoclaved as a component of microbial media with no adverse effects; therefore solutions of A5131 L-Arginine monohydrochloride may be autoclaved.

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