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A5131

Sigma-Aldrich

L-Arginine monohydrochloride

reagent grade, ≥98% (HPLC), powder

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Synonym(s):
(S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
Molecular Weight:
210.66
Beilstein:
3631658
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white

mp

>235 °C

solubility

H2O: 50 mg/mL

application(s)

cell analysis

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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This Item
11039A6969A4599
L-Arginine monohydrochloride reagent grade, ≥98% (HPLC), powder

Sigma-Aldrich

A5131

L-Arginine monohydrochloride

Essential Grade
L-Arginine monohydrochloride BioUltra, ≥99.5% (AT)

Sigma-Aldrich

11039

L-Arginine monohydrochloride

Premium Grade
L-Arginine monohydrochloride

SAFC

A4599

L-Arginine monohydrochloride

-
assay

≥98% (HPLC)

assay

≥99.5% (AT)

assay

98.5-101.0%

assay

≥98.5%

form

powder

form

powder or crystals

form

powder

form

crystalline powder

color

white

color

colorless

color

white

color

-

mp

>235 °C

mp

220-230 °C

mp

226-230 °C

mp

-

solubility

H2O: 50 mg/mL

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

water: 100 mg/mL, clear, colorless

solubility

H2O: 100 mg/mL

Application

L-Arginine monohydrochloride has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster. It has also been used to develop a non-invasive chronic pancreatitis model of rat.

Biochem/physiol Actions

L-Arginine is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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Sigma-Aldrich

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USP

1042601

Arginine hydrochloride

L-Arginine monohydrochloride EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

SAFC

1.01544

L-Arginine monohydrochloride

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Sigma-Aldrich

W381918

L-Arginine

Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
Yang Liu et al.
Biochemical and biophysical research communications, 525(3), 620-625 (2020-03-03)
The circadian clock, a biochemical oscillator, plays a fundamental role in health and diseases. Ferroptosis, a type of regulated cell death driven by oxidative stress, is a prominent feature in iron-induced tissue injury. However, whether an impaired circadian clock contributes
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
Enyong Dai et al.
Nature communications, 11(1), 6339-6339 (2020-12-15)
Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or depletion of Gpx4, an antioxidant enzyme reported as an important ferroptosis suppressor, in the pancreas
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)

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