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A7847

Acridine Orange 10-nonyl bromide

≥90% purity (HPLC), powder or solid

Synonym(s):

10-Nonylacridine orange bromide, 3,6-Bis(dimethylamino)-10-nonylacridinium bromide

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100 MG

$170.10

$170.10

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About This Item

Empirical Formula (Hill Notation):
C26H38BrN3
CAS Number:
75168-11-5
Molecular Weight:
472.50
UNSPSC Code:
12171500
PubChem Substance ID:
329770942
NACRES:
NA.47
MDL number:
MFCD00467605

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Product Name

Acridine Orange 10-nonyl bromide,

SMILES string

[Br-].CCCCCCCCC[n+]1c2cc(ccc2cc3ccc(cc13)N(C)C)N(C)C

InChI

1S/C26H38N3.BrH/c1-6-7-8-9-10-11-12-17-29-25-19-23(27(2)3)15-13-21(25)18-22-14-16-24(28(4)5)20-26(22)29;/h13-16,18-20H,6-12,17H2,1-5H3;1H/q+1;/p-1

InChI key

DRBHTUDHPPBMCD-UHFFFAOYSA-M

assay

≥90% (HPLC)

form

powder or solid

color

orange to red

mp

≥250 °C (lit.)

solubility

ethanol, DMSO: soluble

ε (extinction coefficient)

76-88 at 491-497 nm in methanol

fluorescence

λex 515-523  nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

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1 of 4

This Item
318337235474A8097
Acridine Orange 10-nonyl bromide

Sigma-Aldrich

A7847

Acridine Orange 10-nonyl bromide

Acridine Orange hydrochloride hydrate ≥98% (HPLC)

Sigma-Aldrich

318337

Acridine Orange hydrochloride hydrate

Acridine Orange base Dye content 75 %

Sigma-Aldrich

235474

Acridine Orange base

Acridine Orange hydrochloride solution 10 mg/mL in H2O, ≥95.0% (HPLC)

Sigma-Aldrich

A8097

Acridine Orange hydrochloride solution

color

orange to red

color

orange

color

-

color

orange to red

fluorescence

λex 515-523  nm

fluorescence

-

fluorescence

-

fluorescence

-

solubility

ethanol, DMSO: soluble

solubility

H2O: 0.1%, clear, orange to red

solubility

1 M HCl: 1 mg/mL, clear

solubility

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder or solid

form

powder

form

powder

form

solution

assay

≥90% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

≥95.0% (HPLC)

Application

Metachromatic dye useful as a mitochondrial probe in living cells. This dye has been used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7725
MKCV1413
MKCQ9655
MKCP9479
MKCN0658

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Sonia Alcalá et al.
Nature communications, 11(1), 2682-2682 (2020-05-31)
Pancreatic cancer stem cells (PaCSCs) drive pancreatic cancer tumorigenesis, chemoresistance and metastasis. While eliminating this subpopulation of cells would theoretically result in tumor eradication, PaCSCs are extremely plastic and can successfully adapt to targeted therapies. In this study, we demonstrate
Monika Pichla et al.
Oxidative medicine and cellular longevity, 2020, 9260748-9260748 (2020-05-08)
Parkinson's disease (PD) patients can benefit from antioxidant supplementation, and new efficient antioxidants are needed. The aim of this study was to evaluate the protective effect of selected nitroxide-containing redox nanoparticles (NRNPs) in a cellular model of PD. Antioxidant properties
Roman Krestinin et al.
Biomedicines, 8(10) (2020-10-24)
Mitochondria are key organelles of the cell because their main function is the capture of energy-rich substrates from the cytoplasm and oxidative cleavage with the generation of carbon dioxide and water, processes that are coupled with the synthesis of ATP.
Carlos Sanchez-Martin et al.
Antioxidants & redox signaling, 34(7), 505-516 (2020-05-23)
Aims: TNF receptor-associated protein 1 (TRAP1), the mitochondrial paralog of the heat shock protein 90 (Hsp90) family of molecular chaperones, is required for neoplastic growth in several tumor cell models, where it inhibits succinate dehydrogenase (SDH) activity, thus favoring bioenergetic

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