BCR305

1-Nitropyrene

BCR®, certified reference material

Empirical Formula (Hill Notation):
C16H9NO2
CAS Number:
Molecular Weight:
247.25
Beilstein/REAXYS Number:
1882811
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

certified reference material

Agency/Method

BCR®

mfr. no.

JRC

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

153-155 °C (lit.)

Featured Industry

Environmental
Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[O-][N+](=O)c1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C16H9NO2/c18-17(19)14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9H

Inchi Key

ALRLPDGCPYIVHP-UHFFFAOYSA-N

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General description

1-Nitronaphthalene, belonging to the class of nitrated-polycyclic aromatic hydrocarbons, is persistent in the environment. It is produced from direct sources such as diesel, gasoline exhaust and gas-phase reactions of polycyclic aromatic hydrocarbons (PAHs) with oxides of nitrogen.

Analysis Note

For more information please see:
BCR305

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Eun-Jung Park et al.
Toxicology letters, 184(2), 126-133 (2008-12-02)
Nitropyrene (1-NP) is classified as Group 2B carcinogen and is one of the main components of diesel exhaust particles (DEP), which are generated from incomplete combustion of automobile engines to cause human cancer or inflammatory diseases. Although many reports on...
N Podechard et al.
Toxicology letters, 206(3), 289-299 (2011-08-30)
1-Nitropyrene (1-NP) is a nitro-polycyclic aromatic hydrocarbon (nitro-PAH) present in diesel exhaust and bound to particular matter in urban air. We show that 1-NP and the referent PAH benzo(a)pyrene (BP) induce apoptosis and a lipid accumulation dependent on cytochrome P450...
Helén Andersson et al.
Toxicology, 262(1), 57-64 (2009-05-23)
Both epidemiological and experimental studies suggest that exposure to high levels of air pollution is a risk factor associated with cardiovascular disease. Traffic emission is a major source of exposure to persistent air pollutants such as nitrated polycyclic aromatic hydrocarbons...
Matthew A Ratcliff et al.
Environmental science & technology, 44(21), 8343-8349 (2010-10-05)
The impacts of biodiesel and a continuously regenerated (catalyzed) diesel particle filter (DPF) on the emissions of volatile unburned hydrocarbons, carbonyls, and particle associated polycyclic aromatic hydrocarbons (PAH) and nitro-PAH, were investigated. Experiments were conducted on a 5.9 L Cummins...
Wen-Cheng Chu et al.
Chemical research in toxicology, 22(12), 1938-1947 (2009-12-08)
Cytochrome P450 1a1 (Cyp1a1) is a phase I xenobiotic-metabolizing enzyme, the expression of which is mainly driven by the aryl hydrocarbon receptor (AhR). Cyp1a1 messenger (m)RNA is labile. Our study indicates that 1-nitropyrene (1-NP) highly induced Cyp1a1 protein expression, although...

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