BCR312

2-Nitro-7-methoxynaphtho[2,1-b]furan

BCR®, certified reference material

Empirical Formula (Hill Notation):
C13H9NO4
CAS Number:
Molecular Weight:
243.21
Beilstein/REAXYS Number:
5749492
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

certified reference material

Agency/Method

BCR®

form

neat

mfr. no.

JRC

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Environmental
Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc2c(ccc3oc(cc23)[N+]([O-])=O)c1

InChI

1S/C13H9NO4/c1-17-9-3-4-10-8(6-9)2-5-12-11(10)7-13(18-12)14(15)16/h2-7H,1H3

Inchi Key

BRRIJZQYTOFDAF-UHFFFAOYSA-N

Analysis Note

For more information please see:
BCR312

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
R J Salmon et al.
Carcinogenesis, 10(5), 803-805 (1989-05-01)
2-Nitro-oxaphenalenes are synthetic chemicals which were synthesized in the authors' laboratory. They are the most efficient mutagenic compounds on mammalian cells in culture. They are chemically related to the nitro-naphthofuran family by the displacement of the heterocycle on the naphthalene...
E Touati et al.
Mutation research, 349(2), 193-200 (1996-02-01)
We have studied the global changes which are induced in exponentially growing cultures of Escherichia coli during treatment with 7-methoxy-2-nitronaphtho[2,1-b]furan (R7000), a very potent mutagen and inducer of the SOS response. A two-dimensional analysis of the proteins synthesized in the...
D Le François-Chabas et al.
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 296(6), 283-286 (1983-01-01)
We have studied the in vitro malignant progression of human lymphoid cells by the combined effect of genetic, viral and mutagenic factors. A lymphoblastoid cell line immortalized by Epstein-Barr virus was used; it was derived from a patient suffering from...
J C Maurizis et al.
Xenobiotica; the fate of foreign compounds in biological systems, 15(2), 141-148 (1985-02-01)
The disposition of 7-methoxy-2-nitronaphtho[2,1-b]furan (MNNF), labelled with 14C in the furan ring (label 1) and in the methoxy group (label 2) has been studied in rats and mice. After i.p. administration to rat (5 mg/kg), both labelled species were absorbed...
P Quillardet et al.
Mutation research, 422(2), 237-245 (1998-12-05)
DNA adducts that block replication, induced in vivo by the 5-nitrofuran derivative R7000 (7-methoxy-2-nitronaphtho[2, 1-b]-furan) were mapped, at nucleotide resolution, in a region of the lacI gene of Escherichia coli, using a reiterative primer extension assay [D. Chandrasekhar, B. Van...

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