C19627

Chloroacetic acid

99%

• Synonym(s): Monochloroacetic acid
• Linear Formula: ClCH₂COOH
• CAS Number: 79-11-8
• Molecular Weight: 94.50
• Beilstein: 605438
• EC Number: 201-178-4
• MDL number: MFCD00002683
• PubChem Substance ID: 57653993
• NACRES: NA.21

Properties

• vapor density: 3.26 (vs air)
• Quality Level: 200
• vapor pressure: 0.75 mmHg ( 20 °C)
• assay: 99%
• form: crystals
• bp: 189 °C (lit.)
• mp: 60-63 °C (lit.)
• solubility: water: soluble 3,170 g/L at 10 °C
• SMILES string: OC(=O)CCl
• InChI: 1S/C2H3ClO2/c3-1-2(4)5/h1H2,(H,4,5)
• InChI key: FOCAUTSVDIKZOP-UHFFFAOYSA-N

Description

General description

Chloroacetic acid (CAA, monochloroacetic acid, MCAA) is a halogenated aliphatic carboxylic acid generally used as herbicide and preservative. Its mutagenic effects have been studied in Rattus norvegicus. The rate of degradation of MCA by photocatalysis using TiO₂ at pH 3 is reported to be enhanced under the influence of ozone. It is an irritant that hydrolyzes proteins resulting in degradation of the cells. This property has been applied in treating plantar warts.

Application

Chloroacetic acid may be used to synthesize the following:

• Thiocarbamoylthioacetic acid derivatives.
• 4-Thiazolone derivatives.
• Triazinothiazolone derivatives.
• Water soluble carboxymethyl chitosan.

Packaging

25 g in poly bottle

1 kg in poly bottle

Safety Information

• Pictograms: GHS05,GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331 - H314 - H335 - H400
• Precautionary Statements: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 258.8 °F - closed cup
• Flash Point(C): 126 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves