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C4255

Sigma-Aldrich

Creatinine

anhydrous, ≥98%

Synonym(s):

2-Amino-1-methyl-2-imidazolin-4-one, 2-Imino-1-methylimidazolidin-4-one, 2-Imino-N-methylhydantoin

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10 MG
$14.91
10 G
$19.60
25 G
$34.12
100 G
$178.00
1 KG
$900.60

$14.91

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10 MG
$14.91
10 G
$19.60
25 G
$34.12
100 G
$178.00
1 KG
$900.60

About This Item

Empirical Formula (Hill Notation):
C4H7N3O
CAS Number:
60-27-5
Molecular Weight:
113.12
Beilstein/REAXYS Number:
112061
EC Number:
200-466-7
MDL number:
MFCD00059730
UNSPSC Code:
12352100
PubChem Substance ID:
24892677
NACRES:
NA.22

$14.91

List Price$15.70Save 5%
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Available to ship onMay 20, 2025Details

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grade

anhydrous

Quality Level

200

assay

≥98%

form

powder

mp

295 °C (dec.) (lit.)

SMILES string

CN1CC(=O)N=C1N

InChI

1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

InChI key

DDRJAANPRJIHGJ-UHFFFAOYSA-N

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General description

Creatinine is a breakdown product formed by the degradation of creatine phosphate from muscles. The kidneys extract creatinine from the body by filtering almost all of it from the blood and excreting it in the urine.[1][2] Serum creatinine is the most commonly used indicator for renal functioning.[3] In chemical synthesis, creatinine is used as a heterocyclic nitrogenous compound that produces electron-rich and highly basic creatinine derivatives.[4][5]

Application

Creatinine can be used as:
  • A nitrogen donor building block to prepare nitrogen-containing heterocyclic derivatives.[4][5]
  • A reactant to synthesize donor-acceptor type carbon nitride copolymer, which is used as a photocatalyst in hydrogen production.[4]
  • A starting material to prepare creatol(2-amino-1,5-dihydro-5-hydroxy methylimidazol-4-one) via creatinine chloramine.[6]
  • A reactant to synthesize 3-substituted-3-hydroxyisatins by gold-catalyzed aldolization with various isatins.[7]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

554.0 °F - closed cup

flash_point_c

290 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000452417
0000452418
0000452418
0000452417
0000433028

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Study of Creatinine and its 5-Alkoxy Analogs: Structure and Conformational Studies in the Solid and Solution States by X-Ray Crystallography, NMR, UV and Mass Spectrometry
Arakali AV, et al.
Nucleosides, nucleotides & nucleic acids, 16(12), 2193-2218 (1997)
A review on creatinine measurement techniques
Mohabbati-Kalejahi E, et al.
Talanta, 97, 1-8 (2012)
Constructing creatinine-derived moiety as donor block for carbon nitride photocatalyst with extended absorption and spatial charge separation
Zong X, et al.
Applied Catalysis. B, Environmental, 291 (2021)
Simultaneous determination of creatinine and uric acid in human urine by high-performance liquid chromatography
Zuo Y, et al.
Analytical Sciences, 24(12), 1589-1592 (2008)
Diagnostic accuracy of cystatin C compared to serum creatinine for the estimation of renal dysfunction in adults and children-a meta-analysis
Roos JF, et al.
Clinical Biochemistry, 40(5-6), 383-391 (2007)
View All Related Papers

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How to dissolve creatinine C4255?

    1 answer

    1. This product can be dissolved in water at 50 mg/mL. Please see the sample Certificate of Analysis for solubility information:

      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/C4255-25G0000256899.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

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