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C7254

Sigma-Aldrich

Sodium citrate tribasic dihydrate

≥98%

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Synonym(s):
Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
Molecular Weight:
294.10
Beilstein/REAXYS Number:
6104939
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98%

form

powder

pH

7.5-9 (25 °C, 29.4 g/L)

mp

>300 °C (lit.)

solubility

water: soluble 100 mg/mL

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

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Application


  • Deciphering the orthorhombic crystal structure of a novel NEIL1 nanobody with pseudo-merohedral twinning.: Sodium citrate tribasic dihydrate was utilized as a buffering agent in the crystallization process, facilitating the analysis of a NEIL1 nanobody′s crystal structure, which has implications for understanding DNA repair mechanisms (Thompson et al., 2023).

  • The coiled-coil domain of glycosomal membrane-associated Leishmania donovani PEX14: cloning, overexpression, purification and preliminary crystallographic analysis.: Sodium citrate tribasic dihydrate played a critical role in the purification and crystallization of the coiled-coil domain of PEX14, advancing research on the molecular mechanisms of Leishmania donovani (Shakya and Pratap, 2020).

  • Determination of Mycotoxins in Brown Rice Using QuEChERS Sample Preparation and UHPLC-MS-MS.: This study employs sodium citrate tribasic dihydrate in the QuEChERS method for efficient extraction of mycotoxins, enhancing the accuracy of mycotoxin determination in brown rice samples (Jettanajit and Nhujak, 2016).

  • Electroless Cu Plating on Anodized Al Substrate for High Power LED.: Sodium citrate tribasic dihydrate was used as a complexing agent in the electroless copper plating process, which improved the performance and reliability of high power LEDs (Rha and Lee, 2015).

  • Crystallization and preliminary X-ray analysis of a novel type of lipolytic hydrolase from Bacillus licheniformis.: Sodium citrate tribasic dihydrate was essential in the crystallization of a novel lipolytic hydrolase, aiding in the structural analysis and potential industrial applications of this enzyme (Ju et al., 2014).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Articles

Citrate is one of many cell culture components that affects the performance of serum-free, protein-free and animal protein-free cell culture systems used for biomanufacturing heterologous proteins such as monoclonal antibodies.

Fast assessment of antibody-dependent cell-mediated cytotoxicity (ADCC) and glycoform pattern of a therapeutic antibody rituximab by FcγRIIIa affinity chromatography.

Protocols

Enzymatic Assay of Acid Phosphatase (EC 3.1.3.2)

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