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D4784

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride

≥98% purity (HPLC), powder

Synonym(s):

1,2-Diamino-4,5-methylenedioxybenzene dihydrochloride, 1,3-Benzodioxole-5,6-diamine dihydrochloride, 5,6-Diamino-1,3-benzodioxole dihydrochloride, MDB

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Pack SizeSKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$161.00
50 mg

Available to ship TODAYfromMILWAUKEE

$450.00
100 mg

Available to ship TODAYfromMILWAUKEE

$775.00

About This Item

Empirical Formula (Hill Notation):
C7H8N2O2 · 2HCl
CAS Number:
Molecular Weight:
225.07
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
5641607

$161.00


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Product Name

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, Fluorogenic reagent

Quality Level

assay

≥98% (HPLC)

form

powder

technique(s)

titration: suitable

color

white to orange

mp

247 °C

solubility

H2O: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Nc1cc2OCOc2cc1N

InChI

1S/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H

InChI key

YXEJRYIEFFUUID-UHFFFAOYSA-N

General description

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is a fluorescence tag for α keto acids. It is also required for the derivatization of sialic acids in presence of dilute sulfuric acid. The method allows determination of sialic acids.

Application

Fluorogenic reagent for α-ketoacids.
4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride has been used for the derivatization of sialic acids to analyse them by capillary liquid-chromatography-electrospray ionization/tandem mass spectrometry (CapLC-ESI-MS/MS).

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This Item
6680778450D71607
technique(s)

titration: suitable

technique(s)

-

technique(s)

-

technique(s)

-

color

white to orange

color

white to faint red

color

-

color

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

-

application(s)

-

form

powder

form

solid

form

powder

form

solid

solubility

H2O: 50 mg/mL

solubility

-

solubility

-

solubility

-

assay

≥98% (HPLC)

assay

≥97.0% (HPLC)

assay

≥99.0% (AT)

assay

97%


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Articles

A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.


Capillary Electrophoresis of Carbohydrates (2010)
Determination of the type and quantity of sialic acid in the egg jelly coat of the sea urchin Paracentrotus lividus using capillary LC-ESI-MS/MS.
Yesilyurt B, et al.
Molecular Reproduction and Development, 82, 115-122 (2015)
Determination of sialic acids in immune system cells (coelomocytes) of sea urchin, Paracentrotus lividus, using capillary LC-ESI-MS/MS.
Izzetoglu S, et al.
Fish & Shellfish Immunology, 36, 181-186 (2014)



Global Trade Item Number

SKUGTIN
D4784-50MG04061833585689
D4784-10MG04061832342535
D4784-100MG04061833585672

Questions

  1. When running on HPLC after labeling, which option should be chosen between D4784 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride and 66807 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride?

    1 answer
    1. Both D4784 ,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride and 66807 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride are not marketed as amino acid labeling products. D4784 has a purity of 98% as determined by HPLC, while 66807 has a purity of 97% according to HPLC analysis. Both products are essentially the same.

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