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D4911

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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About This Item

CAS Number:
9011-18-1
MDL number:
MFCD00081551
UNSPSC Code:
12352201
NACRES:
NA.21

Key Documents

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biological source

bacterial (Leuconostoc)

Quality Level

100

form

powder

mol wt

6,500-10,000

composition

Sulfur Content, 16.0-22.0%

color

white to light yellow

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL

storage temp.

room temp

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This Item
D600152423D8787
Dextran sulfate sodium salt from Leuconostoc spp. mol wt 6,500-10,000

Sigma-Aldrich

D4911

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

Sigma-Aldrich

D6001

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. low sulfate content, Mr ~40,000

Sigma-Aldrich

52423

Dextran sulfate sodium salt from Leuconostoc spp.

Dextran sulfate sodium salt from Leuconostoc spp. avg mol wt >500,000 (dextran starting material)

Sigma-Aldrich

D8787

Dextran sulfate sodium salt from Leuconostoc spp.

biological source

bacterial (Leuconostoc)

biological source

bacterial (Leuconostoc mesenteroides)

biological source

(Leuconostoc spp)

biological source

bacterial (Leuconostoc)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

solubility

H2O: 100 mg/mL

form

powder

form

powder

form

powder

form

powder or crystals

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

-

useful pH range

6.0-8 (10 g/L)

useful pH range

6.0-8.0 (1% in water)

useful pH range

6.0-8 (10 g/L)

useful pH range

-

General description

Dextran sulfate is a sulfated polysaccharide, which is negatively charged.[1] It is produced by the esterification of dextran with chlorosulphonic acid.[2] Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli.[3] It is a ribonuclease inhibitor.[4] Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.[2]

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000509748
0000509748
0000505459
0000505460
0000505459

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Parisa Yousefpour et al.
International journal of nanomedicine, 6, 1487-1496 (2011-07-29)
This study deals with the preparation and investigation of a nanoscale delivery system for the anticancer drug doxorubicin (DOX) using its complexation with polyanionic carbohydrate dextran sulfate (DS). Dynamic light scattering, SEM, and zeta potential determination were used to characterize
Radiotherapy, Surgery, and Immunotherapy (2012)
Rheology of Industrial Polysaccharides: Theory and Applications (2012)
Radiotherapy, Surgery, and Immunotherapy (2012)
Valter R M Lombardi et al.
Journal of biomedicine & biotechnology, 2012, 826178-826178 (2012-05-24)
One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new
View All Related Papers

Protocols

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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