E0900000

Ergocalciferol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
Ergosterol irradiated, Ercalciol, Calciferol, Vitamin D2, Irradiated ergosterol
Empirical Formula (Hill Notation):
C28H44O
CAS Number:
Molecular Weight:
396.65
Beilstein/REAXYS Number:
1916682
MDL number:
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency/Method

EP

form

neat

manufacturer/tradename

EDQM

mp

114-118 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

InChI

1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1

InChI key

MECHNRXZTMCUDQ-RKHKHRCZSA-N

Gene Information

human ... VDR(7421)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Ergocalciferol is a form of vitamin D, synthesized by some plants in the presence of UVB light. It can be obtained from diet intake or supplements.

Application

Ergocalciferol may be used as an analytical reference standard for the quantification of the analyte in foods using liquid chromatography coupled to selected reaction monitoring (SRM) mass spectrometry.

Packaging

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Simultaneous determination of cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) in foods by selected reaction monitoring
Dimartino G
Journal of AOAC (Association of Official Analytical Chemists) International, 92(2), 511-517 (2002)
Nutrition in the Prevention and Treatment of Disease (2008)
B L Salle et al.
The American journal of clinical nutrition, 71(5 Suppl), 1317S-1324S (2000-05-09)
During pregnancy, maternal serum concentrations of 25-hydroxyvitamin D, the circulating form of vitamin D, correlate with dietary vitamin D intake. Maternal serum concentrations of 1,25-dihydroxyvitamin D, the hormonal circulating and active form of vitamin D, are elevated during pregnancy; 1,25-dihydroxyvitamin...
H A Bischoff-Ferrari et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 19(2), 265-269 (2004-02-19)
Intracellular 1,25-dihydroxyvitamin D receptor (VDR) is expressed in human skeletal muscle tissue. However, it is unknown whether VDR expression in vivo is related to age or vitamin D status, or whether VDR expression differs between skeletal muscle groups. We investigated...
G Jones et al.
Physiological reviews, 78(4), 1193-1231 (1998-10-28)
The important reactions that occur to the vitamin D molecule and the important reactions involved in the expression of the final active form of vitamin D are reviewed in a critical manner. After an overview of the metabolism of vitamin...
Protocols
This application demonstrates the suitability of the Ascentis Express C18, 5 μm, for the routine analysis of the fat-soluble vitamins D2 and D3 . Structures along with the optimized chromatogram obtained on the Ascentis Express C18, 5 μm are presented.
Read More
Separation of Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard
Read More
Separation of Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard
Read More
Separation of Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard
Read More

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