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E2425000

Ethyl parahydroxybenzoate

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Ethyl 4-hydroxybenzoate, Ethylparaben
Linear Formula:
HOC6H4CO2C2H5
CAS Number:
120-47-8
Molecular Weight:
166.17
Beilstein:
1101972
MDL number:
MFCD00002353
PubChem Substance ID:
329799028
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

parabens

manufacturer/tradename

EDQM

bp

297-298 °C (lit.)

mp

114-117 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCOC(=O)c1ccc(O)cc1

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

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1 of 4

This Item
P3650000M1650000B1217000
Ethyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard

E2425000

Ethyl parahydroxybenzoate

Propyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard

P3650000

Propyl parahydroxybenzoate

Methyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard

M1650000

Methyl parahydroxybenzoate

Butyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard

B1217000

Butyl parahydroxybenzoate

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

API family

parabens

API family

parabens

API family

parabens

API family

butylparaben

bp

297-298 °C (lit.)

bp

-

bp

-

bp

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

PHR1010

Propylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1012

Methylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1022

Butylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

1084000

Butylparaben, United States Pharmacopeia (USP) Reference Standard

1267000

Ethylparaben, United States Pharmacopeia (USP) Reference Standard

1432005

Methylparaben, United States Pharmacopeia (USP) Reference Standard

1577008

Propylparaben, United States Pharmacopeia (USP) Reference Standard

M1650000

Methyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard

P3650000

Propyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard

PHR2668

Ethylparaben Sodium, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 20 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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25G
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Shinshi Oishi
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1845-1849 (2004-09-08)
Parabens are alkyl esters of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in estrogen receptor assays in vitro. In addition butyl and propyl parabens show
S Nicoli et al.
Journal of pharmaceutical sciences, 97(11), 4830-4839 (2008-03-05)
This work aims at investigating the nicotinamide (NA)-ethyl-paraben (EP) binary system both in solution and in the solid state. In particular, the apparent EP solubility in water was studied in the presence of different NA concentrations (between 0.28 and 1.64
Sawsan El Hussein et al.
Experimental dermatology, 16(10), 830-836 (2007-09-12)
Concern is continuously raised about the safety of parabens which are present in most of the cosmetic preparations. In this investigation, methyl-, ethyl-, propyl- and butyl paraben (MP, EP, PP, BP), in a commercial cosmetic lotion, were deposited on human
Suzanne Abbas et al.
Drug metabolism and pharmacokinetics, 25(6), 568-577 (2010-10-12)
Parabens (alkyl esters of 4-hydroxybenzoic acid) are widely used as preservatives in drugs, cosmetic products, and foodstuffs. Safety concerns have recently increased due to the potential health risks associated to exposure to large amounts of these substances. Biotransformation of parabens
Esther Pérez et al.
The Journal of biological chemistry, 279(41), 42584-42592 (2004-08-05)
A few mycobacterial species, most of which are pathogenic for humans, produce dimycocerosates of phthiocerol (DIM) and of glycosylated phenolphthiocerol, also called phenolglycolipid (PGL), two groups of molecules shown to be important virulence factors. The biosynthesis of these molecules is
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