t is not possible to add a purity specification to Eosin Y free acid because no purity tests are performed
E4009
Eosin Y
Dye content ~99%, Powder
Synonym(s):
2′,4′,5′,7′-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43
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About This Item
Empirical Formula (Hill Notation):
C20H8Br4O5
CAS Number:
Molecular Weight:
647.89
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
239-138-3
MDL number:
Colour Index Number:
45380:2
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Product Name
Eosin Y, Dye content ~99 %
InChI key
DBZJJPROPLPMSN-UHFFFAOYSA-N
InChI
1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H
SMILES string
Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br
form
powder
composition
Dye content, ~99%
color
light red to red/pink
solubility
ethanol: 1 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
Looking for similar products? Visit Product Comparison Guide
1 of 4
This Item | E6003 | E4382 | 230251 |
|---|---|---|---|
| color light red to red/pink | color brown | color brown | color orange to very dark orange |
| solubility ethanol: 1 mg/mL | solubility H2O: 1 mg/mL | solubility H2O: 1 mg/mL | solubility spirit: soluble |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| form powder | form powder | form powder | form powder |
| composition Dye content, ~99% | composition Dye content, ≥85% | composition Dye content, ≥90% | composition - |
| storage temp. room temp | storage temp. room temp | storage temp. room temp | storage temp. room temp |
Application
Biochem/physiol Actions
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Antonello Mai et al.
Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)
A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine
An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.
Young LW, et al.
Histochemistry and Cell Biology, 144, 321-321 (2015)
Florian Ménard et al.
Bioorganic & medicinal chemistry, 17(22), 7647-7657 (2009-10-13)
This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and
The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Sun J, et al.
International Journal of Molecular Medicine, 30, 739-739 (2012)
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
Gao Z, et al.
The Journal of Biological Chemistry, 284, 18368-18368 (2009)
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What is the purity level for product E4009 and can it be added to CoA?
1 answer-
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Is there a sample protocol for this product ? There id low solubility of E4009 in even ethanol (1 mg/mL) in that case how to make the usual eosin concentration of 1-5% w/v for use in an H&E staining reaction.
1 answer-
It is not feasible to dissolve catalog number E4009 to a concentration of 1 to 5% in alcohol. For H&E staining or staining sperm for viability, Eosin Y disodium salt is typically used, rather than Eosin Y free acid. Dry dyes, available under catalog numbers E4382 or 861006, are also used, along with various solutions for H&E staining, which also utilize only Eosin Y disodium salt. A 5% Eosin Y solution is available with the catalog number 318906, which is also formulated with Eosin Y disodium salt.
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