ED

Sigma-Aldrich

Ethylenediaminetetraacetic acid

purified grade, ≥98.5%, powder

Synonym(s):
Edathamil, (Ethylenedinitrilo)tetraacetic acid, EDTA, Ethylenedinitrilotetraacetic acid
Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
292.24
Beilstein/REAXYS Number:
1716295
EC Number:
MDL number:
eCl@ss:
39030907
PubChem Substance ID:

Quality Level

grade

purified grade

assay

≥98.5%

form

powder

mp

250 °C (dec.) (lit.)

solubility

water: soluble 0.4 g/L at 20 °C

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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General description

Ethylenediaminetetraacetic acid (EDTA) is an affordable chelating agent. It is an aminopolycarboxylic acid and a hexadentate ligand and forms octahedral complex with cations. Ethylenediaminetetraacetic acid (EDTA) is not recommended for phytoremediation as it can leach into natural water resources. It is used in cosmetics and pharmaceutical industry. It triggers platelet aggregation in pseudothrombocytopenia. In chelation therapy, it elicits protection from oxidative damage during blood and lipid peroxidation and may be useful to treat cardiovascular and carbon tetrachloride induced liver fibrosis.

Application

Ethylenediaminetetraacetic acid may be used:
  • as a component of staining buffer
  • as buffer component for incubating epithelial cell adhesion molecule (EpCAM+) cells with fluorescein isothiocyanate (FITC)-conjugated antibody for cell sorting studies
  • for treating epithelial cells for isolation of mucosal myofibroblasts

Packaging

1 kg in poly bottle
100, 500 g in poly bottle
5 kg in poly drum

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3077 9 / PGIII

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Functional modulation of Crohn?s disease myofibroblasts by anti-tumor necrosis factor antibodies
Di Sabatino A, et al.
Gastroenterology, 133(1), 137-149 (2007)
Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis
Bartholome B, et al.
Faseb Journal, 18(1), 70-80 (2004)
Induced Plant Accumulation of Lithium
Kavanagh L, et al.
Geostandards Newsletter, 8(2), 56-56 (2018)
The phenotypes of pluripotent human hepatic progenitors
Schmelzer E, et al.
Stem Cells, 24(8), 1852-1858 (2006)
Environmental fate and microbial degradation of aminopolycarboxylic acids
Bucheli-Witschel M and Egli T
FEMS Microbiology Reviews, 25(1), 69-106 (2001)

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