F0300000

Folic acid

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): PteGlu, Pteroyl-L-glutamic acid, Vitamin M
• Empirical Formula (Hill Notation): C₁₉H₁₉N₇O₆
• CAS Number: 59-30-3
• Molecular Weight: 441.40
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329799653
• MDL number: MFCD00079305
• Beilstein/REAXYS Number: 100781

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• API family: folic acid
• form: solid
• manufacturer/tradename: EDQM
• technique(s): gas chromatography (GC): suitable, liquid chromatography (LC): suitable
• mp: >285 °C
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChI key: OVBPIULPVIDEAO-LBPRGKRZSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Folic acid, a water-soluble B vitamin, is available in several food products. As it is not generated in the human body, diet is one of the easiest ways to obtain it. It plays a crucial role in the biochemical synthesis and repair of DNA and is used in the management of megaloblastic anemias, neural tube defects such as anencephaly and spina bifida. Pharmaceutical drug forms of folic acid are desirable for supplementing its consumption through the diet.

Application

Folic acid may be used as an European Pharmacopoeia reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1