G0625

D-(+)-Galactose

≥98%

• Synonym(s): Galactose
• Empirical Formula (Hill Notation): C₆H₁₂O₆
• CAS Number: 59-23-4
• Molecular Weight: 180.16
• Beilstein: 1724619
• EC Number: 200-416-4
• MDL number: MFCD00151230
• PubChem Substance ID: 24895019
• NACRES: NA.21

Properties

• biological source: bovine (Ruminant- Cow, Ox, Buffalo)
• Quality Level: 300
• assay: ≥98%
• form: powder
• technique(s): HPLC: suitable
• mp: 168-170 °C (lit.)
• SMILES string: OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
• InChI: 1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1
• InChI key: GZCGUPFRVQAUEE-KCDKBNATSA-N

Description

General description

D-galactose, an aldohexose, is a reducing sugar found naturally in the body. It is present in dairy products and the pectin of some fruits like plums, cherries, and kiwi. D-galactose is also found in certain vegetables, chestnuts, and some herbs.

Application

D-(+)-Galactose has been used:

• as a supplement in SGal media to grow yeast strains to examine the role of different Ssa heat-shock proteins (Hsp70) isoforms in Hsp90 chaperoning functions
• as a carbon source in Biolog (MT2) microplate assay to test the ability of isolates to utilize carbon substrates
• to induce expression of membrane protein-green fluorescent protein (GFP) fusion in yeast

Packaging

100, 500 g in poly bottle

1 kg in poly bottle

5 kg in poly drum

Biochem/physiol Actions

Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.

Metabolism of D-galactose leads to the formation of reactive oxygen species (ROS) and results in oxidative stress and hepatocyte damage.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves