G2164

Gluconolactone

meets USP testing specifications

• Synonym(s): D-(+)-Gluconic acid δ-lactone, δ-Gluconolactone, 1,2,3,4,5-Pentahydroxycaproic acid δ-lactone, D-(+)-Dextronic acid δ-lactone
• Empirical Formula (Hill Notation): C₆H₁₀O₆
• CAS Number: 90-80-2
• Molecular Weight: 178.14
• Beilstein: 83286
• EC Number: 202-016-5
• MDL number: MFCD00006647
• PubChem Substance ID: 24895089
• NACRES: NA.21

Properties

• biological source: corn
• Quality Level: 200
• Agency: USP/NF; meets USP testing specifications
• form: crystalline
• color: white
• mp: 160 °C (dec.) (lit.)
• solubility: water: soluble
• cation traces: Pb: ≤0.001%
• application(s): pharmaceutical (small molecule)
• SMILES string: OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1
• InChI key: PHOQVHQSTUBQQK-SQOUGZDYSA-N

Description

General description

Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.

Application

Gluconolactone has been used:

• to control the acidification kinetics of natural rubber latex (NRL) suspensions
• to study its effects on inhibition and disintegration of collagen fibrils
• to prepare alginate hydrogel

Biochem/physiol Actions

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves