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G7651

Sigma-Aldrich

Glutaraldehyde solution

Grade I, 50% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

Synonym(s):
Glutaric dialdehyde solution, Pentane-1,5-dial
Linear Formula:
OHC(CH2)3CHO
CAS Number:
Molecular Weight:
100.12
Beilstein:
605390
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

type

Grade I

form

liquid

concentration

50% in H2O

technique(s)

electron microscopy: suitable (fixative)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

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General description

Glutaraldehyde is a saturated dialdehyde, which is widely known as a chemical sterilant. Glutaraldehyde solutions comprise both monomers and polymers with a difference in their fixation efficiency. 

Application

Glutaraldehyde solution has been used:
  • along with 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer to fix the concentrated extracellular vesicles (EVs) on concanavalin A for scanning electron microscope (SEM)
  • as a component in a solution to fix the cells to observe its morphology
  • to fix the Escherichia coli cells in aqueous solution to preserve the surface morphology of bacterial cells

Packaging

10 mL in glass bottle

Biochem/physiol Actions

Glutaraldehyde is applicable in biomedical research to fix cells and can also be used to analyze healthy and pathologic red blood cells. It is broadly used to disinfect medical equipment like spirometry tubing, endoscopes, transducers, anesthesia, and respiratory therapy equipment, and reuse laparoscopic disposable plastic trocar. 

Features and Benefits

  • Highly efficient and safe to use with lensed instruments, rubber, or plastics 
  • Non-corrosive to metals
  • Minimum shelf life of 14 days

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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