H0800000

Homatropine hydrobromide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
DL-Homatropine hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo3.2.1oct-3-yl ester hydrobromide, Tropine mandelate hydrobromide
Empirical Formula (Hill Notation):
C16H21NO3 · HBr
CAS Number:
Molecular Weight:
356.25
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

form

neat

CofA

certificate is enclosed in each package

mfr. no.

EDQM

mp

214-217 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3

InChI

1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H

InChI key

DWSGTFTVBLXELC-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.

Application

Homatropine hydrobromide may be used as a test sample for the determination of homatropine hydrobromide in eye drops by second-order derivative spectroscopy.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Other Notes

Sales restrictions may apply.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Richard Roe et al.
Ocular immunology and inflammation, 16(3), 107-108 (2008-06-24)
To describe a patient with HLA-B27-associated anterior uveitis who developed hypotony maculopathy. Visual acuity, biomicroscopic slit-lamp examination, and fluorescein angiogram. Following an episode of acute anterior nongranulomatous HLA-B27-associated uveitis, the patient developed decreased vision, choroidal folds, optic disc edema, and...
Ritika Sachdev et al.
Ocular immunology and inflammation, 19(5), 343-345 (2011-08-13)
To report three cases of bilateral microbial keratitis in eyes with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) induced by highly active antiretroviral therapy (HAART) in patients of acquired immune deficiency syndrome (AIDS). A case series. A detailed clinical...
Brian M Thome et al.
Electrophoresis, 28(10), 1477-1487 (2007-05-12)
True moving bed electrophoresis has been shown to be an effective technique for the bench-scale separation of enantiomers, and it is desired to increase the maximum possible throughput attainable with the process by using electric field gradients. Homatropine enantiomer separations...
Joslyn Sciacca Kirby et al.
Cutis, 84(6), 305-310 (2010-02-20)
Approximately 349 million individuals worldwide are actively infected with syphilis. The incidence of syphilis in North America and Europe is low but has been rising in recent years. The rate of concomitant infection with human immunodeficiency virus (HIV) and syphilis...
Homatropine and psychosis in Weill-Marchesani syndrome.
Anjaiah Madugula et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 45(7), 769-770 (2006-07-13)

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