H1429400

Hydroxyethyl salicylate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
Ethylene glycol salicylate, Salicylic acid ethylene glycol ester, Ethylene glycol monosalicylate, Salicylic acid 2-hydroxyethyl ester
Linear Formula:
HOC6H4COOCH2CH2OH
CAS Number:
Molecular Weight:
182.17
Beilstein/REAXYS Number:
2255685
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

form

neat

CofA

certificate is enclosed in each package

mfr. no.

EDQM

refractive index

n20/D 1.548 (lit.)

bp

166 °C/13 mmHg (lit.)

density

1.244 g/mL at 25 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

SMILES string

OCCOC(=O)c1ccccc1O

InChI

1S/C9H10O4/c10-5-6-13-9(12)7-3-1-2-4-8(7)11/h1-4,10-11H,5-6H2

InChI key

LVYLCBNXHHHPSB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Packaging

Unit quantity: 125 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate.
J Horak et al.
Contact dermatitis, 47(2), 120-121 (2002-11-29)
Miroslav Kucera et al.
Arzneimittel-Forschung, 53(12), 850-856 (2004-01-22)
A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy and...
S E Cross et al.
British journal of clinical pharmacology, 46(1), 29-35 (1998-08-05)
The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controversy as to whether these agents are capable of direct penetration by diffusion through...
Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate.
Susana Córdoba et al.
Dermatitis : contact, atopic, occupational, drug, 22(3), 171-172 (2011-05-17)
Contact dermatitis from hydroxyethyl salicylate.
C Reichert et al.
Contact dermatitis, 33(4), 275-276 (1995-10-01)

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