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I2752

Sigma-Aldrich

L-Isoleucine

reagent grade, ≥98% (HPLC)

Synonym(s):
(2S,3S)-2-Amino-3-methylpentanoic acid
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein:
1721792
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

grade

reagent grade

assay

≥98% (HPLC)

form

powder

application(s)

detection: suitable

color

white

mp

288 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL

SMILES string

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

InChI key

AGPKZVBTJJNPAG-WHFBIAKZSA-N

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Application

L-Isoleucine has been used in capillary feeder (CAFE) assay in a study to determine the consumption of amino acids by Drosophila melanogaster. It has also been used as one of the components of an amino acid mixture, which is used as a supplement for synthetic complete (SC) media.

Packaging

1, 5, 10, 25, 100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

L-Isoleucine is an isomer of L-leucine and is an essential amino acid. It is synthesized from threonine and is a branched-chain hydrophobic amino acid.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions.
Mukai J
Chemical & Pharmaceutical Bulletin, 55(11) (2007)
Michel Fleck, Aram M. Petrosyan
Salts of Amino Acids: Crystallization, Structure and Properties (2014)
Conversion of ammonia or urea into essential amino acids,L-leucine,L-valine, andL-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+
Applied Biochemistry and Biotechnology, 26 (1990)
Large-scale Phenotypic Profiling of Gene Deletion Mutants in Candida glabrata
Fabian Istel
Bio-protocol (2015)
Mated Drosophila melanogaster females consume more amino acids during the dark phase
Shun U
PLoS ONE (2017)

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