Skip to Content
MilliporeSigma
All Photos(4)

Documents

L6026

Sigma-Aldrich

Sodium dodecyl sulfate

BioXtra, ≥99.0% (GC)

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein/REAXYS Number:
3599286
EC Number:
MDL number:
UNSPSC Code:
12161900
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic (oragnic)

Quality Level

description

anionic

product line

BioXtra

assay

≥99.0% (GC)

form

powder

mol wt

micellar avg mol wt 18,000

aggregation number

62

impurities

Insoluble matter, passes filter test

loss

≤0.5% loss on drying, HV, 20-25 °C

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

H2O: 0.1 M, clear, colorless

density

0.496 g/cm3

anion traces

chloride (Cl-): ≤0.05%
phosphate (PO43-): ≤0.0001%

cation traces

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.05 at 280 in H2O at 0.1 M
≤0.08 at 260 in H2O at 0.1 M

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Sodium dodecyl sulfate (SDS) is a well-known anionic detergent widely used in scientific research to denature proteins′ secondary and tertiary structures. It consists of a 12-carbon non-polar chain with a negatively charged sulfate group at the end. SDS is instrumental in denaturing and solubilizing proteins, making it a fundamental component of procedures like polyacrylamide gel electrophoresis, where it helps determine protein molecular weights.Moreover, SDS acts as an organic sodium salt and serves dual roles as a detergent and a protein denaturant. Its distinctive feature is its anionic surfactant nature, characterized by a negative charge. This charge fosters interactions with proteins and lipids, leading to the creation of micellar structures. These micelles are essential for SDS′s capacity to effectively solubilize and stabilize proteins and lipids, enabling their detailed study and manipulation in scientific research. SDS′s amphipathic properties, stemming from a long-chain aliphatic group with an attached negatively charged sulfate, make it a valuable detergent for various biomolecular experiments and studies.

Application

Sodium dodecyl sulfate has been used as a:
  • surfactant to evaluate cytochrome c affinity by using surface plasmon resonance
  • surfactant in particle enhanced immunoassays to inhibit aggregation of particles and to enhance single microsphere coupling
  • biofilm-disrupting agent

Anionic detergent

Features and Benefits

  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for trace levels of Anions and Cations
  • High-purity product ideal for biochemical research purposes

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

wgk_germany

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Biomedical Devices and Their Applications (2013)
Evaluation of cytochrome c affinity to anionic phospholipids by means of surface plasmon resonance
Stepanov G, et al.
Febs Letters, 583(1), 97-100 (2009)
Brandon M Childers et al.
Infection and immunity, 81(11), 4112-4120 (2013-08-28)
Biofilm formation and persistence are essential components for the continued survival of pathogens inside the host and constitute a major contributor to the development of chronic wounds with resistance to antimicrobial compounds. Understanding these processes is crucial for control of
Lonnie J Lucas et al.
Colloids and surfaces. B, Biointerfaces, 49(2), 106-111 (2006-04-20)
Manufacturers of latex immunoassays have typically added surfactants to improve detection sensitivity and prevent non-specific aggregation of microspheres, which may cause both false positives and negatives during diagnostic testing. There is also growing interest in conducting immunoassays in smaller volumes
Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service