L6026

Sigma-Aldrich

Sodium dodecyl sulfate

BioXtra, ≥99.0% (GC)

Synonym(s):
Lauryl sulfate sodium salt, Sodium lauryl sulfate, Dodecyl sulfate sodium salt, SDS, Dodecyl sodium sulfate
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein/REAXYS Number:
3599286
EC Number:
MDL number:
eCl@ss:
39093306
PubChem Substance ID:
NACRES:
NA.21

Quality Level

description

anionic

product line

BioXtra

assay

≥99.0% (GC)

mol wt

micellar avg mol wt 18,000

aggregation number

62

impurities

Insoluble matter, passes filter test

loss

≤0.5% loss on drying, HV, 20-25 °C

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

H2O: 0.1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
phosphate (PO43-): ≤0.0001%

cation traces

Al: ≤0.0005%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.05 at 280 in H2O at 0.1 M
≤0.08 at 260 in H2O at 0.1 M

HLB

40

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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General description

Sodium dodecyl sulfate (SDS) is an anionic surfactant with an ability to denature proteins. It has a long-chain aliphatic group with negatively charged sulfate attached. This makes SDS an amphipathic detergent.

Application

Sodium dodecyl sulfate has been used as a:
  • surfactant to evaluate cytochrome c affinity by using surface plasmon resonance
  • surfactant in particle enhanced immunoassays to inhibit aggregation of particles and to enhance single microsphere coupling
  • biofilm-disrupting agent

Anionic detergent

Packaging

50, 250 g in poly bottle
1 kg in poly bottle

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all

WGK Germany

WGK 2

Flash Point(F)

338.0 °F

Flash Point(C)

170 °C

Certificate of Analysis

Certificate of Origin

Biomedical Devices and Their Applications (2013)
Evaluation of cytochrome c affinity to anionic phospholipids by means of surface plasmon resonance
Stepanov G, et al.
Febs Letters, 583(1), 97-100 (2009)
Lonnie J Lucas et al.
Colloids and surfaces. B, Biointerfaces, 49(2), 106-111 (2006-04-20)
Manufacturers of latex immunoassays have typically added surfactants to improve detection sensitivity and prevent non-specific aggregation of microspheres, which may cause both false positives and negatives during diagnostic testing. There is also growing interest in conducting immunoassays in smaller volumes...
Brandon M Childers et al.
Infection and immunity, 81(11), 4112-4120 (2013-08-28)
Biofilm formation and persistence are essential components for the continued survival of pathogens inside the host and constitute a major contributor to the development of chronic wounds with resistance to antimicrobial compounds. Understanding these processes is crucial for control of...
Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
Pathogen effector proteins are delivered to host cells to suppress plant immunity. However, the mechanisms by which effector proteins function are largely unknown. Here we show that expression of XopP(Xoo), an effector of rice pathogen Xanthomonas oryzae pv. oryzae, in...

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