L6026

Sodium dodecyl sulfate

BioXtra, ≥99.0% (GC)

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• NACRES: NA.21
• PubChem Substance ID: 24896426
• eCl@ss: 39093306
• UNSPSC Code: 12161900
• EC Number: 205-788-1
• MDL number: MFCD00036175
• Beilstein/REAXYS Number: 3599286

Properties

• biological source: synthetic (oragnic)
• Quality Segment: 200
• description: anionic
• product line: BioXtra
• assay: ≥99.0% (GC)
• form: powder
• mol wt: micellar avg mol wt 18,000
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• aggregation number: 62
• impurities: Insoluble matter, passes filter test
• loss: ≤0.5% loss on drying, HV, 20-25 °C
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C
• solubility: H₂O: 0.1 M, clear, colorless
• density: 0.496 g/cm³
• anion traces: chloride (Cl^-): ≤0.05%, phosphate (PO₄^3-): ≤0.0001%
• cation traces: Al: ≤0.0005%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.02%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%
• absorption: ≤0.05 at 280 in H₂O at 0.1 M, ≤0.08 at 260 in H₂O at 0.1 M
• HLB: 40
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• greener alternative category: Aligned
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Sodium dodecyl sulfate (SDS) is a well-known anionic detergent widely used in scientific research to denature proteins′ secondary and tertiary structures. It consists of a 12-carbon non-polar chain with a negatively charged sulfate group at the end. SDS is instrumental in denaturing and solubilizing proteins, making it a fundamental component of procedures like polyacrylamide gel electrophoresis, where it helps determine protein molecular weights.Moreover, SDS acts as an organic sodium salt and serves dual roles as a detergent and a protein denaturant. Its distinctive feature is its anionic surfactant nature, characterized by a negative charge. This charge fosters interactions with proteins and lipids, leading to the creation of micellar structures. These micelles are essential for SDS′s capacity to effectively solubilize and stabilize proteins and lipids, enabling their detailed study and manipulation in scientific research. SDS′s amphipathic properties, stemming from a long-chain aliphatic group with an attached negatively charged sulfate, make it a valuable detergent for various biomolecular experiments and studies.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Application

Sodium dodecyl sulfate has been used as a:

• surfactant to evaluate cytochrome c affinity by using surface plasmon resonance
• surfactant in particle enhanced immunoassays to inhibit aggregation of particles and to enhance single microsphere coupling
• biofilm-disrupting agent

Anionic detergent

Features and Benefits

• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
• Tested for trace levels of Anions and Cations
• High-purity product ideal for biochemical research purposes

Other Notes

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Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318,H412
• pcodes: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges