LightOx™ products are known for their ability to fluoresce under UV light, particularly emitting a blue fluorescence. However, the specific fluorescence characteristics can vary depending on the formulation and intended application of each product. Generally, most LightOx™ products are designed to exhibit blue fluorescence, which is a key feature for their use in various applications, such as in the detection of certain substances or in fluorescence microscopy.
LIGHTOX14
LightOx™14
≥98% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C23H25NO2
CAS Number:
Molecular Weight:
347.45
UNSPSC Code:
12352101
NACRES:
NA.22
Assay:
≥98% (HPLC)
Form:
powder
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assay
≥98% (HPLC)
form
powder
storage temp.
2-8°C
SMILES string
N1(CCC(c2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)(C)C)C(C)C
InChI
1S/C23H25NO2/c1-16(2)24-14-13-23(3,4)20-15-18(9-12-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-12,15-16H,13-14H2,1-4H3,(H,25,26)
InChI key
OCMSZODRCJAGHL-UHFFFAOYSA-N
Related Categories
Application
Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.
Biochem/physiol Actions
Strong ligand for retinoic acid receptor proteins
Features and Benefits
LightOx14 is a synthetic analogue of all-trans-retinoic acid (ATRA) that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx14 can be utilized to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
Other Notes
Chemical Equivalency 1ea=1mg
Legal Information
LightOx is a trademark of LightOx Ltd.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.
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I have bought your LightOX 19, the color under UV light is blue. Could you please tell me that if I use other type, like LighOX 14 or 23, is the color same under same experimental condition? That would be much helpful. Thank you so much.
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