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LIGHTOX23

LightOx™23

≥95% (HPLC)

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1 ea

Available to ship TODAYfromMILWAUKEE

$258.00

About This Item

Empirical Formula (Hill Notation):
C21H25NO2
CAS Number:
2342579-18-2
Molecular Weight:
323.43
UNSPSC Code:
12352101
NACRES:
NA.22

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assay

≥95% (HPLC)

form

powder

storage temp.

2-8°C

SMILES string

N1(CCC(c2c1ccc(c2)c3ccc(cc3)C(=O)O)(C)C)C(C)C

InChI

1S/C21H25NO2/c1-14(2)22-12-11-21(3,4)18-13-17(9-10-19(18)22)15-5-7-16(8-6-15)20(23)24/h5-10,13-14H,11-12H2,1-4H3,(H,23,24)

InChI key

XRGDMRFRHFGVNK-UHFFFAOYSA-N

Application

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Biochem/physiol Actions

Weak ligand for retinoic acid receptor proteins

Features and Benefits

LightOx23 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a weak ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx23 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Chemical Equivalency 1ea=1mg

Legal Information

LightOx is a trademark of LightOx Ltd.

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Sigma-Aldrich

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Sigma-Aldrich

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storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

form

powder

form

powder

form

powder

form

powder

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

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