M1550000

Methylene chloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
Dichloromethane, Methylene chloride
Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein/REAXYS Number:
1730800
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

form

neat

autoignition temp.

1223 °F

expl. lim.

22 %

manufacturer/tradename

EDQM

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−97 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Packaging

Unit quantity: 1.5 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Target Organs

Central nervous system

RIDADR

UN 1593 6.1 / PGIII

WGK Germany

WGK 2

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis

Certificate of Origin

Laura Golsteijn et al.
Environment international, 71, 36-45 (2014-06-28)
The present paper describes a method that accounts for variation in indoor chemical exposure settings and accompanying human toxicity in life cycle assessment (LCA). Metal degreasing with dichloromethane was used as a case study to show method in practice. We...
Angharad M Roberts et al.
Science translational medicine, 7(270), 270ra6-270ra6 (2015-01-16)
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an abundant structural, sensory, and signaling filament in muscle) as a common cause of end-stage dilated cardiomyopathy (DCM) promises new prospects for improving heart failure management. However, realization...
Shinji Kumagai et al.
Occupational and environmental medicine, 70(7), 508-510 (2013-03-16)
The present study was conducted to investigate the relationship between occupational chemical exposure and incidence of cholangiocarcinoma among workers in the offset colour proof-printing section of a small printing company in Osaka, Japan. We identified 51 men who had worked...
K E Mauck et al.
Integrative and comparative biology, 54(2), 193-209 (2014-04-22)
Recent research suggests that plant viruses, and other pathogens, frequently alter host-plant phenotypes in ways that facilitate transmission by arthropod vectors. However, many viruses infect multiple hosts, raising questions about whether these pathogens are capable of inducing transmission-facilitating phenotypes in...
Guilherme Asmar Alencar et al.
The Journal of clinical endocrinology and metabolism, 99(8), E1501-E1509 (2014-04-09)
Primary macronodular adrenal hyperplasia (PMAH) is a rare cause of Cushing's syndrome, usually characterized by functioning adrenal macronodules and increased cortisol production. Familial clustering of PMAH has been described, suggesting an inherited genetic cause for this condition. The aim of...

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