M4627

1-Methylnicotinamide chloride

analytical standard

• Synonym(s): N-Methylnicotinic acid amide chloride
• Linear Formula: C₇H₉N₂OCl
• CAS Number: 1005-24-9
• Molecular Weight: 172.61
• MDL number: MFCD00060042
• UNSPSC Code: 41116107
• PubChem Substance ID: 329817903
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥97.5%
• form: powder
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• color: white
• application(s): forensics and toxicology; veterinary; vitamins, nutraceuticals, and natural products
• format: neat
• SMILES string: [Cl-].C[n+]1cccc(c1)C(N)=O
• InChI: 1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
• InChI key: BWVDQVQUNNBTLK-UHFFFAOYSA-N

Description

General description

1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT) and exhibits antithrombotic and anti-inflammatory effects.

Application

1-Methylnicotinamide chloride may be used as a standard in the quantification of 1-methylnicotinamide in urine samples using ion pairing reverse-phase high performance liquid chromatography (RP-HPLC).[1]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Urinary excretion product of niacin metabolism

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)