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M5279

Supelco

Mebhydroline 1,5-naphthalenedisulfonate salt

analytical standard

Synonym(s):
9-Benzyl-N-methyl-1,2,3,4-tetrahydro-α-carboline
Linear Formula:
C19H20N2 · 1/2C10H8O6S2
CAS Number:
Molecular Weight:
420.52
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

OS(=O)(=O)c1cccc2c(cccc12)S(O)(=O)=O.CN3CCc4c(C3)c5ccccc5n4Cc6ccccc6.CN7CCc8c(C7)c9ccccc9n8Cc%10ccccc%10

InChI

1S/2C19H20N2.C10H8O6S2/c2*1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h2*2-10H,11-14H2,1H3;1-6H,(H,11,12,13)(H,14,15,16)

InChI key

CJUOSBUQOWKEKJ-UHFFFAOYSA-N

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Bamethane hemisulfate salt analytical standard

Supelco

B0382

Bamethane hemisulfate salt

format

neat

format

neat

format

neat

format

neat

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

H1 Histamine receptor antagonist

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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L E Kucheriavykh et al.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 86(12), 1669-1675 (2001-02-24)
Administration of the acetylcholine esterase antagonist aminostigmin increased the number of neutrophils in the estrus phase and the number of lymphocytes in the diestrus phase in rats. Histamine decreased both the neutrophils and lymphocytes at all stages of the estrus
J McEwen et al.
The Medical journal of Australia, 2(11), 523-525 (1982-11-27)
Mebhydrolin napadisylate is an antihistamine marketed in Australia as Fabahistin, and as an ingredient of Fabahistin Plus. Since June, 1973, 11 Australian reports associating this drug with either agranulocytosis or neutropenia have been received by the Adverse Drug Reactions Advisory
J Waitzinger et al.
International journal of clinical pharmacology and therapeutics, 33(7), 373-383 (1995-07-01)
The efficacy of a multiple oral dose treatment with mebhydroline (Omeril coated tablets, 100 mg t.i.d.) was examined in 3 studies which were performed in a randomized, double-blind and placebo-controlled 2-way cross-over design. A second target was to investigate the
[Agranulocytosis associated with mebhydrolin napadisylate (Incidal)].
Y Edoute et al.
Harefuah, 106(5), 208-209 (1984-03-01)
H Shirin et al.
The Annals of pharmacotherapy, 26(12), 1522-1523 (1992-12-01)
To report a case of erythromycin base-induced rash and liver function disturbances. A patient with erythema nodosum and high antistreptolysin-O titers was treated with erythromycin on the assumption that occult streptococcal infection was the cause of the erythema nodosum. Forty-eight

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