M9546

D-Mannitol

BioXtra, ≥98% (HPLC)

• Synonym(s): Mannite
• Empirical Formula (Hill Notation): C₆H₁₄O₆
• CAS Number: 69-65-8
• Molecular Weight: 182.17
• Beilstein: 1721898
• EC Number: 200-711-8
• MDL number: MFCD00064287
• PubChem Substance ID: 24897341
• NACRES: NA.21

Properties

• product line: BioXtra
• Quality Level: 200
• assay: ≥98% (HPLC)
• form: powder
• impurities: ≤0.0005% Phosphorus (P); ≤0.01% Insoluble matter
• ign. residue: ≤0.01%
• mp: 167-170 °C (lit.)
• solubility: H₂O: 1 M, clear, colorless
• anion traces: chloride (Cl^-): ≤0.05%; sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.005%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI key: FBPFZTCFMRRESA-KVTDHHQDSA-N

Description

General description

D-Mannitol is the alcohol form of mannose. Its molar mass is 182 g/mol. Mannitol is present widely in plants, fungi and algae. It is extracted mainly from seaweeds. It is used in food for diabetic patients as it is absorbed slowly. It is commonly used as a stabilizer, humectant, nutritive sweetener and bulking agent in food.

Application

D-Mannitol has been used:

• as a hydroxyl radical inhibitor, to detect the hydroxyl radical generation during the reactive oxygen species (ROS) modification of chromatin
• in [³H]-mannitol permeability assay and also as a component in buffer B for measuring the transmonolayer dilution potentials
• as a component in extracellular recording solution for whole cell patch clamp recordings

Packaging

250 g in poly bottle

1 kg in poly bottle

Biochem/physiol Actions

D-Mannitol is used as an osmotic agent for the treatment of brain swellings.

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M9546.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves