N8878

Nalidixic acid

≥98%

• Synonym(s): 1,4-Dihydro-1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid, 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
• Empirical Formula (Hill Notation): C₁₂H₁₂N₂O₃
• CAS Number: 389-08-2
• Molecular Weight: 232.24
• Beilstein: 750515
• EC Number: 206-864-7
• MDL number: MFCD00006884
• PubChem Substance ID: 24897864
• NACRES: NA.77

Properties

• biological source: synthetic
• Quality Level: 200
• assay: ≥98%
• form: powder
• mp: 227-229 °C (lit.)
• solubility: chloroform: 50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: DNA synthesis | interferes; enzyme | inhibits
• SMILES string: CCN1C=C(C(O)=O)C(=O)c2ccc(C)nc12
• InChI: 1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
• InChI key: MHWLWQUZZRMNGJ-UHFFFAOYSA-N

Description

General description

Chemical structure: quinolone

Packaging

5, 25, 100 g in poly bottle

Application

Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependen)t DNA supercoiling, and chromosome fragmentation.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 - H351
• Precautionary Statements: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves