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NISTRM8398

Human DNA for whole-genome variant assessment (Daughter of Utah/European Ancestry)

NIST SRM 8398

NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

manufacturer/tradename

NIST®

application(s)

pharmaceutical (small molecule)

General description

This reference material consists of a female whole human genome sample of Utah/European ancestry. A unit of RM 8398 consists of a vial containing human genomic DNA extracted from a single large growth of human lymphoblastoid cell line GM12878 (labeled as HG-001). The vial contains approximately 10 μg of genomic DNA, and the DNA is in TE buffer (10 mM TRIS, 1 mM EDTA, pH 8.0).

SRM 8398_cert
SRM 8398 _SDS

Application

Standard Reference Material (SRM) intended for validation, optimization, and process evaluation purposes. Used to assess performance of human genome sequencing variant calling by obtaining estimates of true positives, false positives, and false negatives.
Sequencing applications could include whole genome sequencing, whole exome sequencing, and more targeted sequencing such as gene panels. This genomic DNA is intended to be analyzed in the same way as any other sample a lab would process and analyze extracted DNA.

Features and Benefits

  • RM 8398 is from a human lymphoblastoid cell line and is intended for research use.
  • Details of expiration date, stability, homogeneity, and storage and use instructions are provided on NIST certificate.

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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