P1037

Sigma-Aldrich

Phenol

for molecular biology

Synonym(s):
Hydroxybenzene
Linear Formula:
C6H5OH
CAS Number:
Molecular Weight:
94.11
Beilstein/REAXYS Number:
969616
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.31

Quality Level

grade

for molecular biology

vapor density

3.24 (vs air)

vapor pressure

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

assay

≥99.0% (GC)

form

crystals

autoignition temp.

1319 °F

does not contain

preservative

expl. lim.

8.6 %

impurities

≤2 ppm Mg
≤5 ppm Pb

color

colorless

bp

182 °C (lit.)

mp

40-42 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

suitability

suitable for molecular biology

storage temp.

2-8°C

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554)

Looking for similar products? Visit Product Comparison Guide

Application

Phenol has been used:
  • in solid-phase peptide synthesis
  • as a component of DNA extraction buffer
  • as a component of Alexander′s stain solution

Biochem/physiol Actions

Phenol is majorly used in cosmetics and pharmaceuticals. Phenol pollutes water bodies and inhibits the γ-aminobutyric acid receptor (GABAAR)-coupled chloride ATPase function in the fish brain.

Packaging

Redistilled and packaged under nitrogen in amber bottles.

Signal Word

Danger

hazcat

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

storage_class_code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany

WGK 2

Flash Point(F)

174.2 °F - closed cup

Flash Point(C)

79.0 °C - closed cup

Certificate of Analysis

Certificate of Origin

Effect of phenol on the GABAAR-coupled Cl-/HCO3-ATPase from fish brain: An in vitro approach on the enzyme function
Menzikov SA
Toxicology in vitro, 46(1), 129-136 (2018)
Rapid separation of Arabidopsis male gametophyte developmental stages using a Percoll gradient
Duplakova N, et al.
Nature Protocols, 11(10), 1817-1817 (2016)
Single prokaryotic cell isolation and total transcript amplification protocol for transcriptomic analysis.
Kang Y, et al.
Nature Protocols, 10(7), 974-974 (2015)
Comparative QSAR evidence for a free-radical mechanism of phenol-induced toxicity
Hansch C, et al.
Chemico-Biological Interactions, 127(1), 61-72 (2000)
Zhibo Liu et al.
Nature protocols, 10(9), 1423-1432 (2015-08-28)
Herein we present a general protocol for the functionalization of biomolecules with an organotrifluoroborate moiety so that they can be radiolabeled with aqueous (18)F fluoride ((18)F(-)) and used for positron emission tomography (PET) imaging. Among the β(+)-emitting radionuclides, fluorine-18 ((18)F)...
Protocols
Removal of Ethidium Bromide from DNA by Extraction with Organic Solvents Protocol from Cold Spring Harbor Laboratory Press.
Read More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service