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P2125

Supelco

D-Pantethine

analytical standard

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Synonym(s):
Bis(N-pantothenylamidoethyl) disulfide, LBF factor, Pantethein oxidized form
Empirical Formula (Hill Notation):
C22H42N4O8S2
CAS Number:
Molecular Weight:
554.72
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic (organic)

Quality Level

grade

analytical standard

Assay

≥90%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1

InChI key

DJWYOLJPSHDSAL-ROUUACIJSA-N

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D-Pantethine analytical standard

Supelco

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PHR1228

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Cyanocobalamin pharmaceutical secondary standard, certified reference material

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PHR1234

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Vitamin B12a hydrochloride analytical standard

Supelco

H7126

Vitamin B12a hydrochloride

assay

≥90%

assay

-

assay

-

assay

≥95%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

format

neat

format

neat

format

neat

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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J I Clark et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15185-15189 (1996-12-24)
The effects of pantethine, glutathione, and selected chemical reagents on the anti-aggregation activity of alpha-crystallin was evaluated. Protein aggregation was monitored by light scattering of solutions of denatured beta L-crystallin or alcohol dehydrogenase (ADH). The ratios of beta L-crystallin/alpha-crystallin and
Carl J Balibar et al.
Journal of bacteriology, 193(13), 3304-3312 (2011-05-10)
Coenzyme A (CoA) plays a central and essential role in all living organisms. The pathway leading to CoA biosynthesis has been considered an attractive target for developing new antimicrobial agents with novel mechanisms of action. By using an arabinose-regulated expression
H Nomura et al.
Clinical therapeutics, 18(3), 477-482 (1996-05-01)
We compared the efficacy of two antihyperlipidemic drugs and the efficacy of diet plus exercise therapy in the treatment of patients with moderate hypercholesterolemia. The study included 48 patients with moderate hypercholesterolemia (serum total cholesterol [TC], 250 to 320 mg/dL).
John I Clark
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1617), 20120104-20120104 (2013-03-27)
Cataract, neurodegenerative disease, macular degeneration and pathologies of ageing are often characterized by the slow progressive destabilization of proteins and their self-assembly to amyloid-like fibrils and aggregates. During normal cell differentiation, protein self-assembly is well established as a dynamic mechanism
Marie-France Penet et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(4), 1321-1326 (2008-01-16)
We report that administration of the low-molecular-weight thiol pantethine prevented the cerebral syndrome in Plasmodium berghei ANKA-infected mice. The protection was associated with an impairment of the host response to the infection, with in particular a decrease of circulating microparticles

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